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Exceptional response to chemo-immunotherapy in a patient with HER2-negative, TMB-high metastatic gastric mucinous adenocarcinoma: a case report and literature review.

Gastric mucinous adenocarcinoma (GMC) is a rare subtype of gastric cancer characterized by excessive mucus production, aggressive biological behavior, and poor prognosis, with most patients presenting…

Thérapies de Conversion

Liu, C., Li, X., Qi, Q., Jing, F., Lv, J., Qiu, W., & Wang, S. (2025). Exceptional response to chemo-immunotherapy in a patient with HER2-negative, TMB-high metastatic gastric mucinous adenocarcinoma: a case report and literature review.. Front Immunol, 16, 1713214. https://doi.org/10.3389/fimmu.2025.1713214

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Survival and multi-omics analysis of immunotherapy-based conversion treatment for initially unresectable gastric cancer.

BACKGROUND: Immune checkpoint inhibitors (ICIs) have demonstrated efficacy in the treatment of resectable and advanced gastric cancer. However, their effectiveness in initially unresectable gastric ca…

Thérapies de Conversion

Li, S., Xu, Q., Yu, W., Liu, Z., Cui, X., Wei, M., Shi, D., Zhao, W., Song, X., Zhang, D., Nan, Z., Chu, J., Wang, S., Nie, S., Dai, X., & Liu, L. (2025). Survival and multi-omics analysis of immunotherapy-based conversion treatment for initially unresectable gastric cancer.. Front Immunol, 16, 1753749. https://doi.org/10.3389/fimmu.2025.1753749

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Correction: Immunotherapy in conversion therapy for gastric cancer: current status, progress, and challenges.

[This corrects the article DOI: 10.3389/fonc.2025.1637657.].

Thérapies de Conversion

Su, Y., Zhang, X., & Deng, W. (2025). Correction: Immunotherapy in conversion therapy for gastric cancer: current status, progress, and challenges.. Front Oncol, 15, 1730862. https://doi.org/10.3389/fonc.2025.1730862

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Correction: Conversion therapy with TACE, TKIs, and ICIs for unresectable BCLC stage B and C hepatocellular carcinoma.

[This corrects the article DOI: 10.3389/fimmu.2025.1451965.].

Thérapies de Conversion

Wang, Z., Zhang, C., Yin, J., & Li, N. (2025). Correction: Conversion therapy with TACE, TKIs, and ICIs for unresectable BCLC stage B and C hepatocellular carcinoma.. Front Immunol, 16, 1647890. https://doi.org/10.3389/fimmu.2025.1647890

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Recognizing the Role for Conversion Therapy in Metastatic Esophageal Squamous Cell Cancer (ESCC): A Call for Future Study.

Thérapies de Conversion

Baskin, A. S., & Velotta, J. B. (2025). Recognizing the Role for Conversion Therapy in Metastatic Esophageal Squamous Cell Cancer (ESCC): A Call for Future Study.. Ann Surg Oncol, 32(1), 24-26. https://doi.org/10.1245/s10434-024-16335-0

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Spontaneous Rupture of Hepatocellular Carcinoma: Pathogenesis, Clinical Management, Prognostic Factors, and Future Directions.

Spontaneous rupture of hepatocellular carcinoma (srHCC) is a life-threatening complication with complex pathophysiology and heterogeneous clinical presentations. This review aims to provide an up-to-d…

Thérapies de Conversion

Cheng, Y., Ye, F., & Chen, Y. (2025). Spontaneous Rupture of Hepatocellular Carcinoma: Pathogenesis, Clinical Management, Prognostic Factors, and Future Directions.. J Hepatocell Carcinoma, 12, 2421-2428. https://doi.org/10.2147/JHC.S540510

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Pathological complete response to conversion therapy for lung adenocarcinoma with brain metastasis: a case report.

Lung cancer is the leading cause of cancer mortality worldwide. Fortunately, the advent of precision medicine, which includes targeted therapy and immunotherapy, has significantly improved the surviva…

Thérapies de Conversion

Ran, X., Luo, T., Xiong, J., & Fu, M. (2025). Pathological complete response to conversion therapy for lung adenocarcinoma with brain metastasis: a case report.. Front Oncol, 15, 1625918. https://doi.org/10.3389/fonc.2025.1625918

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Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma.

Advanced hepatocellular carcinoma (HCC) has a poor prognosis. Conversion therapy based on non-surgical local therapy and drug therapy is an effective treatment for unresectable HCC. We report a case o…

Thérapies de Conversion

Mao, J., Zhang, H., Yang, X., Yao, Y., Sun, X., & Yan, Q. (2025). Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma.. Front Oncol, 15, 1627281. https://doi.org/10.3389/fonc.2025.1627281

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A Novel Quadruple Conversion Therapy: Converting Initially Unresectable Hepatocellular Carcinoma to Resectable with pTAE-HAIC, Tyrosine Kinase Inhibitors, and Anti-PD-1 Antibodies.

PURPOSE: The aim of this study was to evaluate the potential of partial transcatheter arterial embolization (pTAE)-hepatic artery infusion chemotherapy (HAIC) in combination with tyrosine kinase inhib…

Thérapies de Conversion

Xiao, J., Li, Q., Zheng, W., Liao, K., Yu, Q., Huang, R., & Zhou, R. (2025). A Novel Quadruple Conversion Therapy: Converting Initially Unresectable Hepatocellular Carcinoma to Resectable with pTAE-HAIC, Tyrosine Kinase Inhibitors, and Anti-PD-1 Antibodies.. J Hepatocell Carcinoma, 12, 1807-1819. https://doi.org/10.2147/JHC.S523755

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Understanding harms associated with gender identity conversion efforts among transgender and nonbinary individuals: The role of preexisting mental well-being.

Affirmation of gender identity is critical for the mental health and overall well-being of transgender and nonbinary (TNB) persons. Gender identity conversion efforts (GICE), an outlawed practice for…

Thérapies de Conversion

Mammadli, T., Call, J., Whitfield, D. L., Holloway, B. T., & Walls, N. E. (2025). Understanding harms associated with gender identity conversion efforts among transgender and nonbinary individuals: The role of preexisting mental well-being.. Int J Transgend Health, 26(1), 157-179. https://doi.org/10.1080/26895269.2024.2333531

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Adaptive transition decisions and identity exploration among transgender and nonbinary persons exposed to gender identity conversion efforts.

INTRODUCTION: Transgender and nonbinary (TNB) persons' healthcare experiences and related transition decisions have received increasing attention in recent years. Growing literature indicates gender n…

Thérapies de Conversion

Mammadli, T., Call, J., Holloway, B. T., Whitfield, D. L., & Walls, N. E. (2025). Adaptive transition decisions and identity exploration among transgender and nonbinary persons exposed to gender identity conversion efforts.. Int J Transgend Health, 26(1), 198-214. https://doi.org/10.1080/26895269.2024.2415681

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Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study.

BACKGROUND: Although immune checkpoint inhibitors (ICIs) and anti-angiogenic drugs have demonstrated effectiveness in treating advanced gastric cancer (GC), their role in neoadjuvant or conversion the…

Thérapies de Conversion

Zhan, Z., Chen, B., Xu, S., Lin, R., Chen, H., Ma, X., Lin, X., Huang, W., Zhuo, C., Chen, Y., & Guo, Z. (2025). Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study.. Front Immunol, 16, 1518217. https://doi.org/10.3389/fimmu.2025.1518217

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