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Hepatic arterial infusion chemotherapy plus sintilimab as conversion therapy for locally advanced hepatocellular carcinoma: a single-center phase II trial.

INTRODUCTION: Patients with locally advanced hepatocellular carcinoma (aHCC) who have macroscopic vascular invasion typically have a poor prognosis. As the understanding of interventional therapy evol…

Thérapies de Conversion

Pan, Y., Wang, X., Peng, C., Zhao, J., Lu, S., Zhang, C., Wang, J., Fu, Y., Zhou, Z., Chen, M., Zhang, Y., & Xu, L. (2026). Hepatic arterial infusion chemotherapy plus sintilimab as conversion therapy for locally advanced hepatocellular carcinoma: a single-center phase II trial.. Int J Surg, 112(4), 9753-60. https://doi.org/10.1097/JS9.0000000000004692

13/01/2026 Lire →

Trans is not the new gay: How psychoanalytic elitism and the rejection of science are creating a repetition of the past.

Psychoanalysis has a troubled history with regard to sexual minorities. Throughout much of the twentieth century, prominent analysts endorsed a highly pathologising and coercive approach to homosexual…

Thérapies de Conversion

D'Angelo, R. (2026). Trans is not the new gay: How psychoanalytic elitism and the rejection of science are creating a repetition of the past.. Int J Psychoanal, 1-23. https://doi.org/10.1080/00207578.2025.2591921

12/01/2026 Lire →

When Resectability Emerges After Systemic Therapy in Hepatocellular Carcinoma: A Proposed Response-Guided Consolidation Framework.

Immune checkpoint inhibitor-based combination therapies have increased the likelihood that a subset of patients with initially unresectable hepatocellular carcinoma (HCC) may achieve sufficient tumor …

Thérapies de Conversion

Cheng, Y., & Xie, K. (2026). When Resectability Emerges After Systemic Therapy in Hepatocellular Carcinoma: A Proposed Response-Guided Consolidation Framework.. J Hepatocell Carcinoma, 13, 613934. https://doi.org/10.2147/JHC.S613934

01/01/2026 Lire →

Case Report: Successful conversion of gallbladder cancer with intrahepatic metastases using camrelizumab combined with gemcitabine and cisplatin.

BACKGROUND: Gallbladder cancer is an extremely aggressive malignant tumor of the digestive system. It presents with no obvious symptoms in its early stages, meaning most patients are already in advanc…

Thérapies de Conversion

Wang, D., Li, Y., Shi, G., Wang, W., Ma, T., Mi, C., Du, Y., Wang, S., Sheng, X., Wang, L., Xu, X., Wang, Y., & Yang, H. (2026). Case Report: Successful conversion of gallbladder cancer with intrahepatic metastases using camrelizumab combined with gemcitabine and cisplatin.. Front Immunol, 17, 1724263. https://doi.org/10.3389/fimmu.2026.1724263

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Multimodal Conversion Therapy Enabling Curative Resection in Giant Hepatocellular Carcinoma with Arteriovenous Fistula: A Case Report.

BACKGROUND: Giant hepatocellular carcinoma (GHCC) with arteriovenous fistula (AVF) is often considered a surgical no-go zone, lacking a standardized conversion therapy. This paper reports a case in wh…

Thérapies de Conversion

Zhong, H., Tan, L., Le, W., Luo, N., Shen, Y., Long, G., Xiong, C., & Tao, H. (2026). Multimodal Conversion Therapy Enabling Curative Resection in Giant Hepatocellular Carcinoma with Arteriovenous Fistula: A Case Report.. J Hepatocell Carcinoma, 13, 599120. https://doi.org/10.2147/JHC.S599120

01/01/2026 Lire →

From centripetal to centrifugal: pathological regression patterns after neoadjuvant or conversion therapy as markers of nodal risk and a framework for future research on individualized lymphadenectomy in gastric cancer.

OBJECTIVE: To analyze the relationship between tumor regression patterns and ypN positivity and explore their implications for postoperative nodal-risk stratification after neoadjuvant or conversion t…

Thérapies de Conversion

Li, N., Liu, P., Guo, J., Wang, J., Zhao, G., Mou, Z., & Mao, J. (2026). From centripetal to centrifugal: pathological regression patterns after neoadjuvant or conversion therapy as markers of nodal risk and a framework for future research on individualized lymphadenectomy in gastric cancer.. Front Immunol, 17, 1766242. https://doi.org/10.3389/fimmu.2026.1766242

01/01/2026 Lire →

Stereotactic body radiation therapy for hepatocellular carcinoma: a comprehensive review.

Hepatocellular carcinoma (HCC) presents significant challenges in modern surgical and radiation oncology, primarily due to biological heterogeneity and the complexities of underlying liver cirrhosis. …

Thérapies de Conversion

Di, Y., Ren, G., Wang, Y., Meng, L., & Li, J. (2026). Stereotactic body radiation therapy for hepatocellular carcinoma: a comprehensive review.. Front Oncol, 16, 1747449. https://doi.org/10.3389/fonc.2026.1747449

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Clinical Efficacy Exploration of Temperature-Sensitive Embolic Agent TACE Combined with HAIC and Targeted/Immunotherapy for Unresectable Primary Liver Cancer.

OBJECTIVE: To evaluate the efficacy and safety of TEM-TACE combined with HAIC and targeted/immunotherapy for the treatment of unresectable primary liver cancer, and to clarify the clinical application…

Thérapies de Conversion

Chen, X., Xiao, H., Lan, X., & Du, C. (2026). Clinical Efficacy Exploration of Temperature-Sensitive Embolic Agent TACE Combined with HAIC and Targeted/Immunotherapy for Unresectable Primary Liver Cancer.. J Hepatocell Carcinoma, 13, 572484. https://doi.org/10.2147/JHC.S572484

01/01/2026 Lire →

Sexual Orientation and Gender Identity Change Efforts Before Age 18: Demographic Correlates and Associations with Mental Health Conditions.

PURPOSE: We examined the associations of sexual orientation and gender identity change efforts (SOGICE), both experienced over the lifetime and before adulthood, with demographic characteristics and a…

Thérapies de Conversion

Xu, Y., Hall, W. J., Wilson, J., & Russell, S. T. (2026). Sexual Orientation and Gender Identity Change Efforts Before Age 18: Demographic Correlates and Associations with Mental Health Conditions.. LGBT Health, 13(2), 85-92. https://doi.org/10.1177/23258292251413624

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From Control to Conversion: Optimizing Systemic Therapy for Curative-Intent Conversion Surgery in Metastatic Gastric Cancer.

Conversion therapy enables curative-intent resection in patients with initially unresectable or metastatic cancers after effective systemic therapy. Recently, advances in systemic therapy with molecul…

Thérapies de Conversion

Han, H. S., & Rha, S. Y. (2026). From Control to Conversion: Optimizing Systemic Therapy for Curative-Intent Conversion Surgery in Metastatic Gastric Cancer.. J Gastric Cancer, 26(1), 146-160. https://doi.org/10.5230/jgc.2026.26.e8

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Safety and efficacy of conversion therapy for metastatic esophageal cancer: exploratory analysis of JCOG1314.

BACKGROUND: Recent advances in multimodal treatments indicate that conversion therapy (CT) is a viable option for metastatic esophageal cancer (EC). JCOG1314 was a randomized phase III trial to confir…

Thérapies de Conversion

Matsuda, S., Tsushima, T., Kawakubo, H., Hironaka, S., Tsubosa, Y., Sakanaka, K., Oguma, J., Kadowaki, S., Tsunoda, S., Hara, H., Koyanagi, K., Yamaguchi, T., Harada, K., Takahashi, M., Minashi, K., Baba, E., Sasaki, K., Machida, R., & Takeuchi, H. (2026). Safety and efficacy of conversion therapy for metastatic esophageal cancer: exploratory analysis of JCOG1314.. Esophagus, 23(1), 111-119. https://doi.org/10.1007/s10388-025-01163-2

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A Qualitative Double Perspective Investigation of Sexual Orientation Change Efforts Among Homosexual Individuals in Tunisia.

Despite the condemnation of the major medical and psychological institutions, which warn of the significant harm associated with sexual orientation change efforts, these practices persist in certain c…

Thérapies de Conversion

Mahjoubi, H., Mtiraoui, A., & Préau, M. (2026). A Qualitative Double Perspective Investigation of Sexual Orientation Change Efforts Among Homosexual Individuals in Tunisia.. J Homosex, 73(5), 1270-1290. https://doi.org/10.1080/00918369.2025.2503407

01/01/2026 Lire →