CredoScientia - Bibliothèque

APOE2 protects against Aβ pathology by improving neuronal mitochondrial function through ERRα signaling.

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disease and apolipoprotein E (APOE) genotypes (APOE2, APOE3, and APOE4) show different AD susceptibility. Previous studies indic…

Neurosciences des Croyances

Ning, Z., Liu, Y., Wan, M., Zuo, Y., Chen, S., Shi, Z., Xu, Y., Li, H., Ko, H., Zhang, J., Xiao, S., Guo, D., & Tang, Y. (2024). APOE2 protects against Aβ pathology by improving neuronal mitochondrial function through ERRα signaling.. Cell Mol Biol Lett, 29(1), 87. https://doi.org/10.1186/s11658-024-00600-x

12/06/2024 Lire →

[For an integrated approach to brain health].

The brain is a vital organ that partly regulates our homeostasis and governs our interactions with the world (i.e. the physical, biological, and social environments). A healthy environment and a peace…

Neurosciences des Croyances

Scantamburlo, G., & Maquet, P. (2024). [For an integrated approach to brain health].. Rev Med Liege, 79(5-6), 311-318.

01/06/2024 Lire →

An Evolutionary Concept Analysis of Pediatric Hospice and Palliative Care.

PURPOSE: This study aimed to clarify the concept of pediatric hospice and palliative care through conceptual analysis. It also sought to identify the differences between related concepts such as pedia…

Neurosciences des Croyances

Lee, J. H., Lee, S. Y., & Cha, K. M. (2024). An Evolutionary Concept Analysis of Pediatric Hospice and Palliative Care.. J Hosp Palliat Care, 27(2), 51-63. https://doi.org/10.14475/jhpc.2024.27.2.51

01/06/2024 Lire →

The relationship between social determinants of health and neurocognitive and mood-related symptoms in the primary brain tumor population: A systematic review.

Social determinants of health (SDOH) impact cancer-related health outcomes, including survival, but their impact on symptoms is less understood among the primary brain tumor (PBT) population. We condu…

Neurosciences des Croyances

Stockdill, M. L., King, A., Johnson, M., Karim, Z., Cooper, D., & Armstrong, T. S. (2024). The relationship between social determinants of health and neurocognitive and mood-related symptoms in the primary brain tumor population: A systematic review.. Neurooncol Pract, 11(3), 226-239. https://doi.org/10.1093/nop/npae016

01/06/2024 Lire →

MRI-Derived AD Signature of Cortical Thinning and Plasma P-Tau217 for Predicting Alzheimer Dementia Among Community-Dwelling Older Adults.

BACKGROUND AND OBJECTIVES: Structural brain MRI and blood-based phosphorylated tau (p-tau) measures are among the least invasive and least expensive Alzheimer's disease (AD) biomarkers to date. The ex…

Neurosciences des Croyances

Yu, L., Wang, T., Hansson, O., Janelidze, S., Lamar, M., Arfanakis, K., Bennett, D. A., Schneider, J. A., & Boyle, P. A. (2024). MRI-Derived AD Signature of Cortical Thinning and Plasma P-Tau217 for Predicting Alzheimer Dementia Among Community-Dwelling Older Adults.. Neurol Clin Pract, 14(3), e200291. https://doi.org/10.1212/CPJ.0000000000200291

01/06/2024 Lire →

An Update on Brain Death/Death by Neurologic Criteria since the World Brain Death Project.

The World Brain Death Project (WBDP) is a 2020 international consensus statement that provides historical background and recommendations on brain death/death by neurologic criteria (BD/DNC) determinat…

Neurosciences des Croyances

Lewis, A. (2024). An Update on Brain Death/Death by Neurologic Criteria since the World Brain Death Project.. Semin Neurol, 44(3), 236-262. https://doi.org/10.1055/s-0044-1786020

01/06/2024 Lire →

Religious Chanting and Self-Related Brain Regions: A Multi-Modal Neuroimaging Study.

This protocol presents a multi-modal neuroimaging approach to explore the potential brain activity associated with repetitive religious chanting, a widespread form of mind training in both Eastern and…

Neurosciences des Croyances

Sik, H. H., Skouras, S., Gao, J., Leung, H. K., Ng, S. M., Lee, K. C., & Wu, B. W. Y. (2024). Religious Chanting and Self-Related Brain Regions: A Multi-Modal Neuroimaging Study.. J Vis Exp. https://doi.org/10.3791/66221

31/05/2024 Lire →

Association of 10 VEGF Family Genes with Alzheimer's Disease Endophenotypes at Single Cell Resolution.

The cell-type specific role of the vascular endothelial growth factors (VEGFs) in the pathogenesis of Alzheimer's disease (AD) is not well characterized. In this study, we utilized a single-nucleus RN…

Neurosciences des Croyances

Wu, Y., Libby, J. B., Dumitrescu, L., De, J. a. g. e. r. . P. L., Menon, V., Schneider, J. A., Bennett, D. A., & Hohman, T. J. (2024). Association of 10 VEGF Family Genes with Alzheimer's Disease Endophenotypes at Single Cell Resolution.. bioRxiv. https://doi.org/10.1101/2024.04.12.589221

22/05/2024 Lire →

Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of neuropathology.

Recent evidence suggests that Alzheimer's disease (AD) genetic risk variants (rs1582763 and rs6591561) of the MS4A locus are genome-wide significant regulators of soluble TREM2 levels such that the mi…

Neurosciences des Croyances

Winfree, R. L., Nolan, E., Dumitrescu, L., Blennow, K., Zetterberg, H., Gifford, K. A., Pechman, K. R., Seto, M., Petyuk, V. A., Wang, Y., Schneider, J., Bennett, D. A., Jefferson, A. L., Hohman, T. J., & Alzheimer’s, D. i. s. e. a. s. e. . N. e. u. r. o. i. m. a. g. i. n. g. . I. n. i. t. i. a. t. i. v. e. *. (2024). Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of neuropathology.. Mol Neurodegener, 19(1), 41. https://doi.org/10.1186/s13024-024-00727-7

18/05/2024 Lire →

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD.

BACKGROUND: Cellular senescence is a hallmark of aging and has been implicated in Alzheimer's disease (AD) pathogenesis. Cholesterol accumulation drives cellular senescence; however, the underlying me…

Neurosciences des Croyances

Wang, S., Li, B., Cai, Z., Hugo, C., Li, J., Sun, Y., Qian, L., Remaley, A. T., Tcw, J., Chui, H. C., Bennett, D. A., Arvanitakis, Z., Kerman, B., & Yassine, H. (2024). Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD.. Res Sq. https://doi.org/10.21203/rs.3.rs-4373201/v1

14/05/2024 Lire →

Spiritual Distress, Hopelessness, and Depression in Palliative Care: Simultaneous Concept Analysis.

Spiritual distress, hopelessness, and depression are concepts that are often used in palliative care. A simultaneous concept analysis (SCA) of these concepts is needed to clarify the terminology used …

Neurosciences des Croyances

Martins, H., Silva, R. S., Bragança, J., Romeiro, J., & Caldeira, S. (2024). Spiritual Distress, Hopelessness, and Depression in Palliative Care: Simultaneous Concept Analysis.. Healthcare (Basel), 12(10). https://doi.org/10.3390/healthcare12100960

07/05/2024 Lire →

Metabolic phenotyping reveals an emerging role of ammonia abnormality in Alzheimer's disease.

The metabolic implications in Alzheimer's disease (AD) remain poorly understood. Here, we conducted a metabolomics study on a moderately aging Chinese Han cohort (n = 1397; mean age 66 years). Conjuga…

Neurosciences des Croyances

Chen, T., Pan, F., Huang, Q., Xie, G., Chao, X., Wu, L., Wang, J., Cui, L., Sun, T., Li, M., Wang, Y., Guan, Y., Zheng, X., Ren, Z., Guo, Y., Wang, L., Zhou, K., Zhao, A., Guo, Q., … Jia, W. (2024). Metabolic phenotyping reveals an emerging role of ammonia abnormality in Alzheimer's disease.. Nat Commun, 15(1), 3796. https://doi.org/10.1038/s41467-024-47897-y

07/05/2024 Lire →