Impact of Mindfulness Meditation on Perceived Stress, Somatic Symptoms and Inflammatory Biomarkers Among Clinical Nurses.

Résumé

BACKGROUND: Clinical nurses face notable chronic stress due to work-related stressors, exacerbated by the COVID-19 pandemic, leading to somatic symptoms and low-grade inflammation. Mindfulness meditation has shown promise in reducing stress and improving health outcomes, but its effects on somatic symptoms and inflammatory biomarkers in nurses remain underexplored.AIM: To assess the impact of mindfulness meditation on somatic symptoms and inflammatory biomarkers such as leptin, interleukin-6, and tumor necrosis factor-α among nurses. To explore the secondary effects on perceived stress and trait mindfulness because of the complex interlinked association with the primary outcomes of interest.METHODOLOGY: A randomized controlled trial was conducted with 102 nurses randomly assigned to a meditation group (8-week mindfulness meditation program) or a non-meditation group. Data were collected using self-report questionnaires (Mindfulness Attention Awareness Scale, Perceived Stress Scale, Patient Health Questionnaire-15) and blood samples for biomarker analysis at baseline and post-intervention.FINDINGS: The meditation group demonstrated notable reductions in perceived stress (p