CredoScientia - Bibliothèque

Comparison of outcomes between surgery and non-surgery after conversion therapy for advanced gastric cancer with unresectable factors: a systematic review and meta-analysis.

BACKGROUND: Advanced gastric cancer (AGC) with unresectable factors presents a significant treatment challenge. Conventional treatments such as systemic chemotherapy, radiotherapy, and immunotherapy c…

Thérapies de Conversion

Wu, J., Du, X., He, Y., & Xian, S. (2025). Comparison of outcomes between surgery and non-surgery after conversion therapy for advanced gastric cancer with unresectable factors: a systematic review and meta-analysis.. BMC Gastroenterol, 25(1), 371. https://doi.org/10.1186/s12876-025-03969-x

14/05/2025 Lire →

Hepatic artery infusion chemotherapy combined with camrelizumab and apatinib as conversion therapy for patients with unresectable hepatocellular carcinoma: a single-arm exploratory trial.

BACKGROUND: The development of systemic therapy, including targeted drugs and immune checkpoint inhibitors, has significantly improved the prognosis of patients with advanced unresectable hepatocellul…

Thérapies de Conversion

Yalikun, K., Li, Z., Zhang, J., Chang, Z., Li, M., Sun, Z., Liu, Z., Yang, Y., Xu, L., Li, L., Zhang, C., Sun, P., Zhong, J., Cui, K., Shi, X., Zhang, B., & Zhao, L. (2025). Hepatic artery infusion chemotherapy combined with camrelizumab and apatinib as conversion therapy for patients with unresectable hepatocellular carcinoma: a single-arm exploratory trial.. BMC Cancer, 25(1), 838. https://doi.org/10.1186/s12885-025-14250-5

07/05/2025 Lire →

Donafenib and sintilimab combined with hepatic arterial infusion chemotherapy for unresectable hepatocellular carcinoma: a prospective, single-arm phase II trial (DoHAICs study).

BACKGROUND: Donafenib demonstrates superior survival benefits and safety compared to sorafenib. Hepatic arterial infusion chemotherapy (HAIC) proves effective for large unresectable hepatocellular car…

Thérapies de Conversion

Gao, W., Pan, Z. L., Zhao, X. H., Yang, L., Cao, J. B., Li, D. Y., Zheng, H. J., Liu, C., Li, G. T., Bao, X., Liu, X. M., Zhang, W. H., Zhu, X. L., Xiao, B. H., Song, T. Q., Li, Q., Lu, W., Xing, W. G., & Zhang, W. (2025). Donafenib and sintilimab combined with hepatic arterial infusion chemotherapy for unresectable hepatocellular carcinoma: a prospective, single-arm phase II trial (DoHAICs study).. EClinicalMedicine, 83, 103217. https://doi.org/10.1016/j.eclinm.2025.103217

01/05/2025 Lire →

Transcription Factor-Based Gene Therapy Enables Functional Repair of Rat Following Chronic Ischemic Stroke.

OBJECTIVE: In vivo transcription factor (TF) -mediated gene therapy through astrocyte-to-neuron (AtN) conversion has shown therapeutic effects on rodent and non-human primate cortical ischemic injury …

Thérapies de Conversion

Wang, T., Wang, X., Liu, S., Li, M., Wan, K., Zheng, J., Liao, K., Wang, J., Zou, K., Wang, L., Xu, H., Lei, W., Chen, G., & Li, W. (2025). Transcription Factor-Based Gene Therapy Enables Functional Repair of Rat Following Chronic Ischemic Stroke.. CNS Neurosci Ther, 31(5), e70448. https://doi.org/10.1111/cns.70448

01/05/2025 Lire →

Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review.

This review discusses the evolving role of radiotherapy (RT) in the surgical treatment of pancreatic ductal adenocarcinoma (PDAC). Despite advancements in multidisciplinary treatment, PDAC continues t…

Thérapies de Conversion

Yasuda, S., Nagai, M., Nakamura, K., Matsuo, Y., & Sho, M. (2025). Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review.. Ann Gastroenterol Surg, 9(3), 418-428. https://doi.org/10.1002/ags3.70012

01/05/2025 Lire →

Conversion Therapy Exposure and Elevated Cardiovascular Disease Risk.

IMPORTANCE: Sexual orientation and gender identity change efforts (SOGICE), commonly known as conversion therapy, persist across the United States despite having been discredited due to their harmful …

Thérapies de Conversion

Gibb, J. K., Schrock, J. M., Smith, M. S., D'Aquila, R. T., McDade, T. W., & Mustanski, B. (2025). Conversion Therapy Exposure and Elevated Cardiovascular Disease Risk.. JAMA Netw Open, 8(5), e258745. https://doi.org/10.1001/jamanetworkopen.2025.8745

01/05/2025 Lire →

Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer.

BACKGROUND/AIM: The approval of first-line nivolumab plus chemotherapy marks a breakthrough in treating human epidermal growth factor receptor 2 (HER2)-negative unresectable advanced gastric and gastr…

Thérapies de Conversion

Hojo, Y., Tomita, T., Igeta, M., Murakami, M., Kohno, S., Nakao, E., Kitayama, Y., Nakamura, T., Kurahashi, Y., Ishida, Y., Hirota, S., Shinzaki, S., & Shinohara, H. (2025). Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer.. Anticancer Res, 45(5), 2091-2102. https://doi.org/10.21873/anticanres.17583

01/05/2025 Lire →

A questionnaire survey to explore the current treatment policies adopted for patients with advanced hepatocellular carcinoma at board-certified HPB training institutions in Japan: A JSHBPS project study 2023, Part 1.

PURPOSE: To clarify the views of expert hepatobiliary surgeons on the management of advanced hepatocellular carcinoma (HCC) in real-world clinical practice.METHODS: A questionnaire survey was conducte…

Thérapies de Conversion

Shindoh, J., Matsumura, M., Okubo, S., Okada, T., Hashimoto, M., Nakamura, M., & Ohtsuka, M. (2025). A questionnaire survey to explore the current treatment policies adopted for patients with advanced hepatocellular carcinoma at board-certified HPB training institutions in Japan: A JSHBPS project study 2023, Part 1.. J Hepatobiliary Pancreat Sci, 32(5), 360-373. https://doi.org/10.1002/jhbp.12139

01/05/2025 Lire →

A deep learning-based clinical-radiomics model predicting the treatment response of immune checkpoint inhibitors (ICIs)-based conversion therapy in potentially convertible hepatocelluar carcinoma patients: a tumor marker prognostic study.

BACKGROUND: The majority of patients with hepatocellular carcinoma (HCC) miss the opportunity of radical resection, making immune check-point inhibitors (ICIs)-based conversion therapy a primary optio…

Thérapies de Conversion

Lin, Z., Wang, W., Yan, Y., Ma, Z., Xiao, Z., & Mao, K. (2025). A deep learning-based clinical-radiomics model predicting the treatment response of immune checkpoint inhibitors (ICIs)-based conversion therapy in potentially convertible hepatocelluar carcinoma patients: a tumor marker prognostic study.. Int J Surg, 111(5), 3342-3355. https://doi.org/10.1097/JS9.0000000000002322

01/05/2025 Lire →

Potential Harm in the Psychological Treatment of Sexual and Gender Minority Youth.

Sexual and gender minority (SGM) individuals show disproportionately high rates of mental distress relative to their cisgender, heterosexual peers resulting from minority stress, or unique identity-re…

Thérapies de Conversion

Pinciotti, C. M., Cusack, C. E., Rodriguez-Seijas, C., Lorenzo-Luaces, L., Dyk, I. S. V., & Galupo, M. P. (2025). Potential Harm in the Psychological Treatment of Sexual and Gender Minority Youth.. Res Child Adolesc Psychopathol, 53(5), 715-727. https://doi.org/10.1007/s10802-024-01268-9

01/05/2025 Lire →

Preoperative assessment and prognostic prediction of gastric cancer patients with peritoneal metastasis using F-FDG PET/CT before conversion surgery.

BACKGROUND: Conversion therapy followed by conversion surgery (CS) can improve the prognosis of gastric cancer (GC) patients with peritoneal metastasis (PM). However, patients benefit differently. The…

Thérapies de Conversion

Peng, Y., Shi, M., Xiong, D., Lu, S., Miao, Y., Yuan, H., Yan, C., Zhu, Z., Li, B., Yang, Z., & Hu, J. (2025). Preoperative assessment and prognostic prediction of gastric cancer patients with peritoneal metastasis using F-FDG PET/CT before conversion surgery.. EJNMMI Res, 15(1), 46. https://doi.org/10.1186/s13550-025-01244-4

21/04/2025 Lire →

Single centre experience with conversion surgery for advanced and metastatic gastric cancer in Slovakia.

Conversion surgery (CS) following systemic chemotherapy (SCT) has been suggested as a promising strategy for improving prognosis of patients with advanced gastric carcinoma (GC). The evidence, however…

Thérapies de Conversion

Palaj, J., Kečkéš, �. �., Marek, V., Dyttert, D., Sabol, M., Durdík, �. �., & Waczulíková, I. (2025). Single centre experience with conversion surgery for advanced and metastatic gastric cancer in Slovakia.. Sci Rep, 15(1), 13381. https://doi.org/10.1038/s41598-025-98656-y

18/04/2025 Lire →