CredoScientia - Bibliothèque

Precision conversion of colorectal cancer lung metastases: A personalized quadruplet regimen integrating photodynamic therapy with targeted, immunotherapy, and chemotherapy.

SIGNIFICANCE: Colorectal cancer (CRC) has a high incidence and mortality rate, with lung metastasis being the second most common site. Current treatments have limited efficacy, and novel approaches ar…

Thérapies de Conversion

Han, Q., Gao, L., Wang, Y., Wang, Z., He, L., Liu, B., Hu, J., Xu, B., & Chen, H. (2026). Precision conversion of colorectal cancer lung metastases: A personalized quadruplet regimen integrating photodynamic therapy with targeted, immunotherapy, and chemotherapy.. Photodiagnosis Photodyn Ther, 58, 105362. https://doi.org/10.1016/j.pdpdt.2026.105362

01/04/2026 Lire →

Surgery-centered integrated strategies for personalized hepatocellular carcinoma care.

Hepatocellular carcinoma (HCC) remains a major global health burden characterized by late-stage diagnosis and high postoperative recurrence rates. This review presents a surgery-centered precision man…

Thérapies de Conversion

Cui, Y., Du, Z., Xu, J., Gu, L., Du, J., Wang, M., & Yang, T. (2026). Surgery-centered integrated strategies for personalized hepatocellular carcinoma care.. Cancer Biol Med. https://doi.org/10.20892/j.issn.2095-3941.2026.0045

30/03/2026 Lire →

Gemcitabine-cisplatin plus durvalumab in advanced intrahepatic cholangiocarcinoma: effectiveness outcomes and characterization of the tumor microenvironment.

BACKGROUND/AIMS: Most patients with intrahepatic cholangiocarcinoma (ICC) present with advanced, unresectable disease. Although gemcitabine-cisplatin (GC) plus durvalumab improves outcomes, its real-w…

Thérapies de Conversion

Xu, J., Ji, Y., Feng, M., Zhang, Z., & Yu, D. (2026). Gemcitabine-cisplatin plus durvalumab in advanced intrahepatic cholangiocarcinoma: effectiveness outcomes and characterization of the tumor microenvironment.. Hepatol Int. https://doi.org/10.1007/s12072-026-11070-y

24/03/2026 Lire →

Efficacy and Safety of Conversion Surgery Versus Non-Surgical Treatment for Initially Unresectable Esophageal Cancer: A Systematic Review and Meta-Analysis.

Thérapies de Conversion

Chen, L., Zhao, J., & Luo, X. (2026). Efficacy and Safety of Conversion Surgery Versus Non-Surgical Treatment for Initially Unresectable Esophageal Cancer: A Systematic Review and Meta-Analysis.. J Gastrointest Cancer, 57(1). https://doi.org/10.1007/s12029-026-01440-y

23/03/2026 Lire →

[Recent advances in hepatic arterial infusion chemotherapy for conversion therapy of hepatocellular carcinoma].

Hepatocellular carcinoma(HCC) is one of the common malignant tumors in China. Most patients are diagnosed at an intermediate or advanced stage, thereby losing the opportunity for curative treatment. T…

Thérapies de Conversion

Chen, M. S., & Xiao, R. (2026). [Recent advances in hepatic arterial infusion chemotherapy for conversion therapy of hepatocellular carcinoma].. Zhonghua Yi Xue Za Zhi, 106(10), 891-896. https://doi.org/10.3760/cma.j.cn112137-20251021-02699

17/03/2026 Lire →

[Sequential surgery following conversion therapy based on the combination of immune checkpoint inhibitors and antiangiogenic targeted drugs alters the treatment landscape and outcomes for advanced hepatocellular carcinoma].

Hepatocellular carcinoma (HCC) often presents insidiously, and the majority of patients are diagnosed at an advanced stage, missing the opportunity for curative surgery. In recent years, breakthrough …

Thérapies de Conversion

Tang, H. W., Jiang, H. X., Cao, Y. B., & Lu, S. C. (2026). [Sequential surgery following conversion therapy based on the combination of immune checkpoint inhibitors and antiangiogenic targeted drugs alters the treatment landscape and outcomes for advanced hepatocellular carcinoma].. Zhonghua Yi Xue Za Zhi, 106(10), 885-890. https://doi.org/10.3760/cma.j.cn112137-20251116-02982

17/03/2026 Lire →

LGBTQ+ Ayahuasca Retreat Experience is Associated with Benefits to Mental Health, Quality of Life, and Spiritual Well-Being: A Prospective, Naturalistic Study.

Sexual and gender minority (SGM) individuals experience disproportionately high rates of depression, anxiety, trauma, and discrimination, yet remain underrepresented in psychedelic research. This pros…

Spiritualité Saine et Résilience Thérapies de Conversion

Lowe, M. X., Darby, Q. A., Kalcheff-Korn, S., & Jackson, H. (2026). LGBTQ+ Ayahuasca Retreat Experience is Associated with Benefits to Mental Health, Quality of Life, and Spiritual Well-Being: A Prospective, Naturalistic Study.. J Psychoactive Drugs, 1-12. https://doi.org/10.1080/02791072.2026.2644858

13/03/2026 Lire →

Optimal duration of adjuvant targeted-immunotherapy in patients with initially unresectable hepatocellular carcinoma with portal vein tumor thrombus following successful conversion therapy.

BACKGROUND: The management of initially unresectable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) has been revolutionized by conversion therapy combining locoregional and syst…

Thérapies de Conversion

Wang, L., Feng, J. K., Zhou, B., Liu, Z. H., Gong, L., Yan, M. L., Zhao, H. T., Jiang, Y. B., Shi, J., Guo, W. X., Yuan, Y., Lu, C. D., & Cheng, S. Q. (2026). Optimal duration of adjuvant targeted-immunotherapy in patients with initially unresectable hepatocellular carcinoma with portal vein tumor thrombus following successful conversion therapy.. Oncologist, 31(4). https://doi.org/10.1093/oncolo/oyag054

09/03/2026 Lire →

Expert consensus on the use of immune checkpoint inhibitors in the liver transplant setting: Guidance from the Liver Transplant Committee of the Italian Association for the Study of the Liver (AISF).

Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for advanced hepatocellular carcinoma, increasing opportunities for downstaging and conversion to liver transplantation (LT…

Thérapies de Conversion

Ponziani, F. R., Giannelli, V., Marrone, G., Martini, S., Morelli, M. C., Pagano, D., Baroni, G. S., Germani, G., Burra, P., & Toniutto, P. (2026). Expert consensus on the use of immune checkpoint inhibitors in the liver transplant setting: Guidance from the Liver Transplant Committee of the Italian Association for the Study of the Liver (AISF).. Am J Transplant. https://doi.org/10.1016/j.ajt.2026.02.024

03/03/2026 Lire →

Apparent Long-Term Cure Following Conversion Therapy for Initially Unresectable Pancreatic Ductal Adenocarcinoma: A Case Report.

Locally advanced pancreatic ductal adenocarcinoma (LA-PDAC) is increasingly managed with neoadjuvant chemotherapy with the aim of tumour downstaging and potential conversion to resection. LA-PDAC is t…

Thérapies de Conversion

Florou, E., Zen, Y., Srinivasan, P., & Prachalias, A. (2026). Apparent Long-Term Cure Following Conversion Therapy for Initially Unresectable Pancreatic Ductal Adenocarcinoma: A Case Report.. Cureus, 18(3), e105912. https://doi.org/10.7759/cureus.105912

01/03/2026 Lire →

Conversion Therapy for cT4b and M1 Esophageal Squamous Cell Carcinoma: A Comprehensive Systematic Review.

Conversion therapy, defined as curative-intent surgery or chemoradiotherapy after induction therapy, is gaining attention in patients with initially unresectable esophageal squamous cell carcinoma due…

Thérapies de Conversion

Booka, E., & Takeuchi, H. (2026). Conversion Therapy for cT4b and M1 Esophageal Squamous Cell Carcinoma: A Comprehensive Systematic Review.. Ann Gastroenterol Surg, 10(2), 294-304. https://doi.org/10.1002/ags3.70104

01/03/2026 Lire →

Chemotherapy combined with pembrolizumab in advanced gallbladder cancer with subsequent radical resection: A case report.

Gallbladder cancer is often diagnosed at an advanced stage, preventing radical surgical intervention. Combined with its highly aggressive nature, this results in a generally poor prognosis. Although a…

Thérapies de Conversion

Hu, Y., Wei, Y., Liu, X., Shen, L., Wang, Y., & Yuan, J. (2026). Chemotherapy combined with pembrolizumab in advanced gallbladder cancer with subsequent radical resection: A case report.. ILIVER, 5(1), 100219. https://doi.org/10.1016/j.iliver.2026.100219

01/03/2026 Lire →