Transcription Factor-Based Gene Therapy Enables Functional Repair of Rat Following Chronic Ischemic Stroke.

OBJECTIVE: In vivo transcription factor (TF) -mediated gene therapy through astrocyte-to-neuron (AtN) conversion has shown therapeutic effects on rodent and non-human primate cortical ischemic injury …

Thérapies de Conversion
Wang, T., Wang, X., Liu, S., Li, M., Wan, K., Zheng, J., Liao, K., Wang, J., Zou, K., Wang, L., Xu, H., Lei, W., Chen, G., & Li, W. (2025). Transcription Factor-Based Gene Therapy Enables Functional Repair of Rat Following Chronic Ischemic Stroke.. CNS Neurosci Ther, 31(5), e70448. https://doi.org/10.1111/cns.70448

Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review.

This review discusses the evolving role of radiotherapy (RT) in the surgical treatment of pancreatic ductal adenocarcinoma (PDAC). Despite advancements in multidisciplinary treatment, PDAC continues t…

Thérapies de Conversion
Yasuda, S., Nagai, M., Nakamura, K., Matsuo, Y., & Sho, M. (2025). Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review.. Ann Gastroenterol Surg, 9(3), 418-428. https://doi.org/10.1002/ags3.70012

Conversion Therapy Exposure and Elevated Cardiovascular Disease Risk.

IMPORTANCE: Sexual orientation and gender identity change efforts (SOGICE), commonly known as conversion therapy, persist across the United States despite having been discredited due to their harmful …

Thérapies de Conversion
Gibb, J. K., Schrock, J. M., Smith, M. S., D'Aquila, R. T., McDade, T. W., & Mustanski, B. (2025). Conversion Therapy Exposure and Elevated Cardiovascular Disease Risk.. JAMA Netw Open, 8(5), e258745. https://doi.org/10.1001/jamanetworkopen.2025.8745

Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer.

BACKGROUND/AIM: The approval of first-line nivolumab plus chemotherapy marks a breakthrough in treating human epidermal growth factor receptor 2 (HER2)-negative unresectable advanced gastric and gastr…

Thérapies de Conversion
Hojo, Y., Tomita, T., Igeta, M., Murakami, M., Kohno, S., Nakao, E., Kitayama, Y., Nakamura, T., Kurahashi, Y., Ishida, Y., Hirota, S., Shinzaki, S., & Shinohara, H. (2025). Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer.. Anticancer Res, 45(5), 2091-2102. https://doi.org/10.21873/anticanres.17583

A questionnaire survey to explore the current treatment policies adopted for patients with advanced hepatocellular carcinoma at board-certified HPB training institutions in Japan: A JSHBPS project study 2023, Part 1.

PURPOSE: To clarify the views of expert hepatobiliary surgeons on the management of advanced hepatocellular carcinoma (HCC) in real-world clinical practice.METHODS: A questionnaire survey was conducte…

Thérapies de Conversion
Shindoh, J., Matsumura, M., Okubo, S., Okada, T., Hashimoto, M., Nakamura, M., & Ohtsuka, M. (2025). A questionnaire survey to explore the current treatment policies adopted for patients with advanced hepatocellular carcinoma at board-certified HPB training institutions in Japan: A JSHBPS project study 2023, Part 1.. J Hepatobiliary Pancreat Sci, 32(5), 360-373. https://doi.org/10.1002/jhbp.12139

A deep learning-based clinical-radiomics model predicting the treatment response of immune checkpoint inhibitors (ICIs)-based conversion therapy in potentially convertible hepatocelluar carcinoma patients: a tumor marker prognostic study.

BACKGROUND: The majority of patients with hepatocellular carcinoma (HCC) miss the opportunity of radical resection, making immune check-point inhibitors (ICIs)-based conversion therapy a primary optio…

Thérapies de Conversion
Lin, Z., Wang, W., Yan, Y., Ma, Z., Xiao, Z., & Mao, K. (2025). A deep learning-based clinical-radiomics model predicting the treatment response of immune checkpoint inhibitors (ICIs)-based conversion therapy in potentially convertible hepatocelluar carcinoma patients: a tumor marker prognostic study.. Int J Surg, 111(5), 3342-3355. https://doi.org/10.1097/JS9.0000000000002322

Potential Harm in the Psychological Treatment of Sexual and Gender Minority Youth.

Sexual and gender minority (SGM) individuals show disproportionately high rates of mental distress relative to their cisgender, heterosexual peers resulting from minority stress, or unique identity-re…

Thérapies de Conversion
Pinciotti, C. M., Cusack, C. E., Rodriguez-Seijas, C., Lorenzo-Luaces, L., Dyk, I. S. V., & Galupo, M. P. (2025). Potential Harm in the Psychological Treatment of Sexual and Gender Minority Youth.. Res Child Adolesc Psychopathol, 53(5), 715-727. https://doi.org/10.1007/s10802-024-01268-9

Spatial inference of Culex pipiens abundance and biting activity distribution in the Netherlands using citizen science.

BACKGROUND: The expanding geographical spread of mosquito-borne diseases (MBDs) has intensified the need for effective mosquito surveillance. Additional surveillance, particularly of species such as C…

Contrôle Coercitif et Mécanismes d'Emprise
Abourashed, A., Cerecedo-Iglesias, C., Dellar, M., Palmer, J. R. B., & Bartumeus, F. (2025). Spatial inference of Culex pipiens abundance and biting activity distribution in the Netherlands using citizen science.. Parasit Vectors, 18(1), 162. https://doi.org/10.1186/s13071-025-06774-3

Challenging the Continued Usefulness of Social Media Recruitment for Surveys of Hidden Populations of People Who Use Opioids.

Historically, recruiting research participants through social media facilitated access to people who use opioids, capturing a range of drug use behaviors. The current rapidly changing online landscape…

Études fondées sur les communautés Reddit
Nesoff, E. D., Palamar, J. J., Li, Q., Li, W., & Martins, S. S. (2025). Challenging the Continued Usefulness of Social Media Recruitment for Surveys of Hidden Populations of People Who Use Opioids.. J Med Internet Res, 27, e63687. https://doi.org/10.2196/63687

Smoking cessation support preferences among people released from smoke-free prisons in Queensland, Australia.

PURPOSE: This study aims to investigate previous use, awareness and preferences for various forms of cessation support among a sample of people recently released from smoke-free prisons in Queensland,…

Soutien par les pairs en ligne et transitions religieuses chez les adolescents
Heit, K., Snoswell, C. L., Holland, A., Kinner, S. A., Coomber, R., de, A. n. d. r. a. d. e. . D., & Puljević, C. (2025). Smoking cessation support preferences among people released from smoke-free prisons in Queensland, Australia.. Int J Prison Health (2024), 21(2), 197-205. https://doi.org/10.1108/IJOPH-11-2023-0075

The Significance of Political Grief: An Examination Through Major Global Events.

The impact of political events, actions, policies and ideologies can be both profound and far reaching, with many people experiencing significant losses and major grief as a consequence. There is now …

Sortie, Deuil, Déconversion et Reconstruction Identitaire
Thompson, N., Corless, I., Cox, G., Gallagher, D., Harris, D., Ho, A. H. Y., Monahan, J., Price, D., Sofka, C., & van, W. i. e. l. i. n. k. . J. (2025). The Significance of Political Grief: An Examination Through Major Global Events.. Omega (Westport), 302228251337278. https://doi.org/10.1177/00302228251337278

Social Listening for Patient Experiences With Stopping Extended-Release Buprenorphine: Content Analysis of Reddit Messages.

BACKGROUND: Discontinuation of buprenorphine as a medication for opioid use disorder (MOUD) necessitates careful tapering to reduce opioid withdrawal and relapse. With a half-life of 43-60 days, bupre…

Études fondées sur les communautés Reddit
Gilbert, M. K., Daughton, A. R., Chilcoat, H. D., Laffont, C. M., Strafford, S., & DeVeaugh-Geiss, A. M. (2025). Social Listening for Patient Experiences With Stopping Extended-Release Buprenorphine: Content Analysis of Reddit Messages.. J Med Internet Res, 27, e71245. https://doi.org/10.2196/71245