Self-reported experiences and perspectives on using psychedelics to manage opioid use among participants of two Reddit communities.

BACKGROUND AND AIMS: The opioid crisis continues to exert a tremendous toll in North America, with existing interventions often falling short of addressing ongoing needs. Psychedelics are emerging as …

Études fondées sur les communautés Reddit
Krawczyk, N., Miller, M., Gu, E. Y., Irvine, N., Ramirez, E., Santaella-Tenorio, J., Lippincott, T., Bogenschutz, M., Bunting, A. M., & Meacham, M. C. (2025). Self-reported experiences and perspectives on using psychedelics to manage opioid use among participants of two Reddit communities.. Addiction. https://doi.org/10.1111/add.16767

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.

BACKGROUND: A significant proportion of individuals maintain healthy cognitive function despite having extensive Alzheimer's disease (AD) pathology, known as cognitive resilience. Understanding the mo…

Neurosciences des Croyances
Castanho, I., Yeganeh, P. N., Boix, C. A., Morgan, S. L., Mathys, H., Prokopenko, D., White, B., Soto, L. M., Pegoraro, G., Shah, S., Ploumakis, A., Kalavros, N., Bennett, D. A., Lange, C., Kim, D. Y., Bertram, L., Tsai, L. H., Kellis, M., Tanzi, R. E., & Hide, W. (2025). Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.. bioRxiv. https://doi.org/10.1101/2025.01.13.632801

Chinese expert consensus on sequential surgery following conversion therapy based on combination of immune checkpoint inhibitors and antiangiogenic targeted drugs for advanced hepatocellular carcinoma (2024 edition).

Up to half of hepatocellular carcinoma (HCC) cases are diagnosed at an advanced stage, for which effective treatment options are lacking, resulting in a poor prognosis. Over the past few years, the co…

Thérapies de Conversion
Tang, H., Zhang, W., Cao, J., Cao, Y., Bi, X., Zhao, H., Zhang, Z., Liu, Z., Wan, T., Lang, R., Sun, W., Du, S., Yang, Y., Lu, Y., Zeng, D., Wu, J., Duan, B., Lin, D., Li, F., … Editorial, B. o. a. r. d. . o. f. . t. h. e. . C. h. i. n. e. s. e. . J. o. u. r. n. a. l. . o. f. . H. e. p. a. t. o. b. i. l. i. a. r. y. . S. u. r. g. e. r. y. (2025). Chinese expert consensus on sequential surgery following conversion therapy based on combination of immune checkpoint inhibitors and antiangiogenic targeted drugs for advanced hepatocellular carcinoma (2024 edition).. Biosci Trends, 18(6), 505-524. https://doi.org/10.5582/bst.2024.01394

Advances in systemic therapy leading to conversion surgery for advanced hepatocellular carcinoma.

Recently, a systemic therapy for advanced hepatocellular carcinoma (HCC) has been developed. The regimen for unresectable HCC varies and includes single or multi-tyrosine kinase inhibitors, monoclonal…

Thérapies de Conversion
Hakoda, H., Ichida, A., & Hasegawa, K. (2025). Advances in systemic therapy leading to conversion surgery for advanced hepatocellular carcinoma.. Biosci Trends, 18(6), 525-534. https://doi.org/10.5582/bst.2024.01372

Analysis of Reddit Discussions on Motivational Factors for Physical Activity: Cross-Sectional Study.

BACKGROUND: Despite the ample benefits of physical activity (PA), many individuals do not meet the minimum PA recommended by health organizations. Structured questionnaires and interviews are commonly…

Études fondées sur les communautés Reddit
Shmueli-Scheuer, M., Silverman, Y., Halperin, I., & Gepner, Y. (2025). Analysis of Reddit Discussions on Motivational Factors for Physical Activity: Cross-Sectional Study.. J Med Internet Res, 27, e54489. https://doi.org/10.2196/54489

Efficacy of Combined PD-1 Inhibitor and Bevacizumab in Unresectable Liver Metastasis of MSI-H Colorectal Cancer: A Case Report.

BACKGROUND Programmed death 1 (PD-1) inhibitors have demonstrated limited effectiveness in patients with microsatellite instability-high (MSI-H) colorectal cancer (CRC). Recent studies suggest that th…

Thérapies de Conversion
Wang, Q., Zhong, J., Wang, Y., Bao, J., Li, S., & Yang, L. (2025). Efficacy of Combined PD-1 Inhibitor and Bevacizumab in Unresectable Liver Metastasis of MSI-H Colorectal Cancer: A Case Report.. Am J Case Rep, 26, e946757. https://doi.org/10.12659/AJCR.946757

Treatment outcomes and prognostic factors in patients with colorectal cancer and synchronous lung metastases in the conversion therapy era.

PURPOSE: The Japanese Grade Classification based on the status of pulmonary and mesenteric nodal metastases and the presence of extrapulmonary metastases had a prognostic value in patients with colore…

Thérapies de Conversion
Nozawa, H., Suzuki, N., Tsushima, T., Murono, K., Sasaki, K., Emoto, S., Fujishiro, M., Sato, M., & Ishihara, S. (2025). Treatment outcomes and prognostic factors in patients with colorectal cancer and synchronous lung metastases in the conversion therapy era.. Int J Colorectal Dis, 40(1), 9. https://doi.org/10.1007/s00384-024-04799-1

Applying Natural Language Processing Techniques to Map Trends in Insomnia Treatment Terms on the r/Insomnia Subreddit: Infodemiology Study.

BACKGROUND: People share health-related experiences and treatments, such as for insomnia, in digital communities. Natural language processing tools can be leveraged to understand the terms used in dig…

Études fondées sur les communautés Reddit
Cummins, J. A., Gottlieb, D. J., Sofer, T., & Wallace, D. A. (2025). Applying Natural Language Processing Techniques to Map Trends in Insomnia Treatment Terms on the r/Insomnia Subreddit: Infodemiology Study.. J Med Internet Res, 27, e58902. https://doi.org/10.2196/58902

Mindfulness-Oriented Professional Resilience (MOPR) Training to Reduce Compassion Fatigue in Healthcare Workers: A Pilot Study.

: Compassion Fatigue (CF) is a critical issue among healthcare professionals, exacerbated by exposure to trauma and chronic workplace stress. This pilot study evaluates the effectiveness of a Mindfuln…

Psychothérapies et Approches Cliniques
D'Antoni, F., Matiz, A., & Crescentini, C. (2025). Mindfulness-Oriented Professional Resilience (MOPR) Training to Reduce Compassion Fatigue in Healthcare Workers: A Pilot Study.. Healthcare (Basel), 13(2). https://doi.org/10.3390/healthcare13020092

Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study.

BACKGROUND: The increasing use of social media to share lived and living experiences of substance use presents a unique opportunity to obtain information on side effects, use patterns, and opinions on…

Études fondées sur les communautés Reddit
Das, S., Ge, Y., Guo, Y., Rajwal, S., Hairston, J., Powell, J., Walker, D., Peddireddy, S., Lakamana, S., Bozkurt, S., Reyna, M., Sameni, R., Xiao, Y., Kim, S., Chandler, R., Hernandez, N., Mowery, D., Wightman, R., Love, J., … Sarker, A. (2025). Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study.. J Med Internet Res, 27, e66220. https://doi.org/10.2196/66220

[Psychopathological features of obsessive-compulsive disorder with religious content in young men].

OBJECTIVE: To identify clinical and psychopathological features of obsessive-compulsive disorder (OCD) with religious content in young men and develop a clinical typology of these conditions.MATERIAL …

Psychopathologie de la Religion et de la Spiritualité TOC et Scrupulosité Religieuse
Popovich, U. O., Alekseeva, A. G., & Kaleda, V. G. (2025). [Psychopathological features of obsessive-compulsive disorder with religious content in young men].. Zh Nevrol Psikhiatr Im S S Korsakova, 125(10. Vyp. 2), 32-37. https://doi.org/10.17116/jnevro202512510232

Examining Organ Donor Gratitude Letters as a Novel Approach to Boost Organ Donor Registrations in South Korea.

With recent drops in organ donation support exacerbating the organ shortage, the current investigation sought to explore the potential for organ donor gratitude letters to be utilized in organ donatio…

TOC et Scrupulosité Religieuse
Chung, M., Han, J., Miller, M. J., & Quick, B. L. (2025). Examining Organ Donor Gratitude Letters as a Novel Approach to Boost Organ Donor Registrations in South Korea.. J Health Commun, 30(10-12), 583-593. https://doi.org/10.1080/10810730.2025.2588342