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Imaging-defined complete response to immune checkpoint inhibitors predicts durable survival in advanced hepatocellular carcinoma.

BACKGROUND: Immune checkpoint inhibitors (ICIs) have revolutionized advanced hepatocellular carcinoma (HCC) treatment, yet complete responses (CRs) remain rare, and their long-term outcomes are poorly…

Thérapies de Conversion

Shao, Y., Yuan, J., Liu, Y., & Wang, F. (2025). Imaging-defined complete response to immune checkpoint inhibitors predicts durable survival in advanced hepatocellular carcinoma.. Front Oncol, 15, 1687449. https://doi.org/10.3389/fonc.2025.1687449

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Interstitial Cystitis Chatter: A Qualitative Evaluation of Bladder Instillation Online.

OBJECTIVE: To qualitatively assess the perception and experiences of bladder instillation for interstitial cystitis among women on Reddit, a widely used anonymous social media platform.METHODS: "r/int…

Études fondées sur les communautés Reddit

Wong, R., Licari, L. C., Bologna, E., & Adelstein, S. (2025). Interstitial Cystitis Chatter: A Qualitative Evaluation of Bladder Instillation Online.. Urology, 195, 23-27. https://doi.org/10.1016/j.urology.2024.10.051

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Mothers with Breastfeeding Difficulty Report Increased Depressive Symptoms and Impaired Maternal-Infant Bonding on Social Media.

Protection against postpartum depression is a commonly cited maternal benefit of breastfeeding. However, recent studies have found that negative breastfeeding experiences may actually increase the ri…

Études fondées sur les communautés Reddit

Wright, E. A., Mehta, A., & Nelson, A. L. (2025). Mothers with Breastfeeding Difficulty Report Increased Depressive Symptoms and Impaired Maternal-Infant Bonding on Social Media.. J Womens Health (Larchmt), 34(2), 251-260. https://doi.org/10.1089/jwh.2024.0151

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Can large language models address unmet patient information needs and reduce provider burnout in the management of thyroid disease?

BACKGROUND: Patient electronic messaging has increased clinician workload contributing to burnout. Large language models can respond to these patient queries, but no studies exist on large language mo…

Études fondées sur les communautés Reddit

Raghunathan, R., Jacobs, A. R., Sant, V. R., King, L. J., Rothberger, G., Prescott, J., Allendorf, J., Seib, C. D., Patel, K. N., & Suh, I. (2025). Can large language models address unmet patient information needs and reduce provider burnout in the management of thyroid disease?. Surgery, 177, 108859. https://doi.org/10.1016/j.surg.2024.06.075

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Exceptional response to chemo-immunotherapy in a patient with HER2-negative, TMB-high metastatic gastric mucinous adenocarcinoma: a case report and literature review.

Gastric mucinous adenocarcinoma (GMC) is a rare subtype of gastric cancer characterized by excessive mucus production, aggressive biological behavior, and poor prognosis, with most patients presenting…

Thérapies de Conversion

Liu, C., Li, X., Qi, Q., Jing, F., Lv, J., Qiu, W., & Wang, S. (2025). Exceptional response to chemo-immunotherapy in a patient with HER2-negative, TMB-high metastatic gastric mucinous adenocarcinoma: a case report and literature review.. Front Immunol, 16, 1713214. https://doi.org/10.3389/fimmu.2025.1713214

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Survival and multi-omics analysis of immunotherapy-based conversion treatment for initially unresectable gastric cancer.

BACKGROUND: Immune checkpoint inhibitors (ICIs) have demonstrated efficacy in the treatment of resectable and advanced gastric cancer. However, their effectiveness in initially unresectable gastric ca…

Thérapies de Conversion

Li, S., Xu, Q., Yu, W., Liu, Z., Cui, X., Wei, M., Shi, D., Zhao, W., Song, X., Zhang, D., Nan, Z., Chu, J., Wang, S., Nie, S., Dai, X., & Liu, L. (2025). Survival and multi-omics analysis of immunotherapy-based conversion treatment for initially unresectable gastric cancer.. Front Immunol, 16, 1753749. https://doi.org/10.3389/fimmu.2025.1753749

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Multidisciplinary management of surgery and postoperative recurrence in stage IV gallbladder cancer following conversion therapy: a case report.

A 61-year-old female patient presented with a 10-day history of right upper abdominal pain and was subsequently diagnosed with stage IV gallbladder cancer based on preoperative imaging and pathologica…

Thérapies de Conversion

Cheng, J., Li, X., Ren, C., Yu, S., Huang, H., Zhou, S., & Dai, J. (2025). Multidisciplinary management of surgery and postoperative recurrence in stage IV gallbladder cancer following conversion therapy: a case report.. Front Oncol, 15, 1749491. https://doi.org/10.3389/fonc.2025.1749491

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Exploring Social and Structural Determinants of Substance Use Among Sexual and Gender Minority Adults in the United States.

PurposeTo identify key social and structural factors associated with hazardous alcohol and problematic drug use among sexual and gender minority (SGM) adults.MethodsWe conducted a cross-sectional seco…

Thérapies de Conversion

Zhang, C., Tang, Y., Kniffen, W., & Liu, Y. (2025). Exploring Social and Structural Determinants of Substance Use Among Sexual and Gender Minority Adults in the United States.. J Int Assoc Provid AIDS Care, 24, 23259582251409855. https://doi.org/10.1177/23259582251409855

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Evaluation of Combined Lipiodol and Epirubicin-Loaded Drug-Eluting Bead Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma.

PURPOSE: To evaluate the short-term clinical efficacy, side effects and risk factors affecting the clinical effectiveness of the combination of lipidol and epirubicin-loaded drug-eluting bead transart…

Thérapies de Conversion

Song, D., Feng, X., Zhou, Y., Cai, Y., & Xue, T. (2025). Evaluation of Combined Lipiodol and Epirubicin-Loaded Drug-Eluting Bead Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma.. J Hepatocell Carcinoma, 12, 2723-2733. https://doi.org/10.2147/JHC.S565056

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The impact of clergy sexual abuse on spirituality and health: A systematic scoping review of the literature.

Sexual abuse perpetrated by clergy or other Church leaders can cause harm to the spirituality of people who are subject to this abuse, which also has impacts on their overall health. We conducted a sy…

Violences Sexuelles en Contexte Sectaire

Durkin, J., Zordan, R., Bullen, M., Pavich, N., Thomas, P. T. B., Lethborg, C., Holder, W., Jolly, M., Dreise, D., & Fleming, D. (2025). The impact of clergy sexual abuse on spirituality and health: A systematic scoping review of the literature.. PLoS One, 20(4), e0317821. https://doi.org/10.1371/journal.pone.0317821

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[Organised abuse in the GDR - A Secondary Analysis of the Victims' Perspective].

OBJECTIVE: Organiszed abuse (OA) is a form of long-lasting, mostly sexualized violence against children, youth, or women by networked perpetrators for financial and power-related enrichment. Individua…

Violences Sexuelles en Contexte Sectaire

Laue, P., & Strauß, B. (2025). [Organised abuse in the GDR - A Secondary Analysis of the Victims' Perspective].. Psychother Psychosom Med Psychol, 75(1), 9-19. https://doi.org/10.1055/a-2422-0496

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Role of attachment style in the association between childhood adversities and non-suicidal self-injury among young adults: a multigroup structural equation study.

BACKGROUND: Non-suicidal self-injury (NSSI) is a significant health concern among adolescents and young adults, often resulting from adverse childhood experiences (ACEs). Dissociation, post-traumatic …

Dissociation Structurelle et Troubles Dissociatifs

Rossi, R., Jannini, T. B., Socci, V., Pacitti, F., Rossi, A., & Di, L. o. r. e. n. z. o. . G. (2025). Role of attachment style in the association between childhood adversities and non-suicidal self-injury among young adults: a multigroup structural equation study.. Gen Psychiatr, 38(2), e101277. https://doi.org/10.1136/gpsych-2023-101277

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