Conversion study of hepatocellular carcinoma using HAIC combined with lenvatinib and PD-1/L1 immunotherapy under the guidance of BCLC staging.

OBJECTIVE: This study aimed to assess the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) combined with lenvatinib and immunotherapy and explore its potential as a conversion trea…

Thérapies de Conversion
Zhang, W., Zhao, X., Gao, W., Si, T., Zou, Q., Yang, X., Xing, W., & Yu, H. (2025). Conversion study of hepatocellular carcinoma using HAIC combined with lenvatinib and PD-1/L1 immunotherapy under the guidance of BCLC staging.. Front Immunol, 16, 1596864. https://doi.org/10.3389/fimmu.2025.1596864

Rare Gingival Metastasis Occurring After Conversion Therapy Followed by Resection of Initially Unresectable Hepatocellular Carcinoma: A Case Report.

Gingival metastases from hepatocellular carcinoma (HCC) are exceedingly rare and highly prone to be misdiagnosed without biopsy. Here, we report an initially unresectable HCC patient who received effe…

Thérapies de Conversion
Zhan, J., Huang, H., Zhan, T., Liu, X., & Cheng, Q. (2025). Rare Gingival Metastasis Occurring After Conversion Therapy Followed by Resection of Initially Unresectable Hepatocellular Carcinoma: A Case Report.. J Hepatocell Carcinoma, 12, 705-713. https://doi.org/10.2147/JHC.S514983

Development of a Nomogram for Prognostic Prediction of Large Hepatocellular Carcinoma With HBV After TACE Combined Conversion Therapy.

BACKGROUND: Surgical resection (SR) following transarterial chemoembolization (TACE) is a promising option for large hepatocellular carcinoma (LHCC) with HBV, and identification of these patients at h…

Thérapies de Conversion
Xu, W., Ding, X., Xu, Y., Zhang, Y., Xu, H., Guo, L., & Li, L. (2025). Development of a Nomogram for Prognostic Prediction of Large Hepatocellular Carcinoma With HBV After TACE Combined Conversion Therapy.. Hepat Med, 17, 1-12. https://doi.org/10.2147/HMER.S481334

Conversion therapy combined with ALPPS for the treatment of intrahepatic cholangiocarcinoma: a case report.

RATIONALE: Intrahepatic cholangiocarcinoma (ICC) is a highly malignant liver tumor with limited treatment options for advanced cases. Conversion therapy combining immunotherapy, targeted therapy, and …

Thérapies de Conversion
Tian, H., He, Q., & Wan, C. (2025). Conversion therapy combined with ALPPS for the treatment of intrahepatic cholangiocarcinoma: a case report.. Front Oncol, 15, 1542955. https://doi.org/10.3389/fonc.2025.1542955

Local-region treatment comparison following conversion therapy of hepatocellular carcinoma: a period and age-dependent analysis.

BACKGROUND: Transarterial chemoembolization (TACE) is a potential conversion therapeutic strategy for unresectable hepatocellular carcinoma (uHCC). However, therapeutic options following conversion th…

Thérapies de Conversion
Hu, J., Zhao, S., Zuo, M., Li, C. H., Yao, W., Yang, X., Xing, W., & Song, P. (2025). Local-region treatment comparison following conversion therapy of hepatocellular carcinoma: a period and age-dependent analysis.. Ther Adv Med Oncol, 17, 17588359251316665. https://doi.org/10.1177/17588359251316665

Systemic Treatment for Unresectable Hepatocellular Carcinoma: A Surgeon's Perspective.

In recent years, the standard treatment for hepatocellular carcinoma (HCC) has changed dramatically due to the emergence of potent systemic treatment options. These advanced therapies have led to incr…

Thérapies de Conversion
Zhu, X. D., Zhao, L., Li, B., Cheng, Y., & Sun, H. C. (2025). Systemic Treatment for Unresectable Hepatocellular Carcinoma: A Surgeon's Perspective.. J Hepatocell Carcinoma, 12, 399-413. https://doi.org/10.2147/JHC.S504457

Understanding harms associated with gender identity conversion efforts among transgender and nonbinary individuals: The role of preexisting mental well-being.

Affirmation of gender identity is critical for the mental health and overall well-being of transgender and nonbinary (TNB) persons. Gender identity conversion efforts (GICE), an outlawed practice for…

Thérapies de Conversion
Mammadli, T., Call, J., Whitfield, D. L., Holloway, B. T., & Walls, N. E. (2025). Understanding harms associated with gender identity conversion efforts among transgender and nonbinary individuals: The role of preexisting mental well-being.. Int J Transgend Health, 26(1), 157-179. https://doi.org/10.1080/26895269.2024.2333531

Adaptive transition decisions and identity exploration among transgender and nonbinary persons exposed to gender identity conversion efforts.

INTRODUCTION: Transgender and nonbinary (TNB) persons' healthcare experiences and related transition decisions have received increasing attention in recent years. Growing literature indicates gender n…

Thérapies de Conversion
Mammadli, T., Call, J., Holloway, B. T., Whitfield, D. L., & Walls, N. E. (2025). Adaptive transition decisions and identity exploration among transgender and nonbinary persons exposed to gender identity conversion efforts.. Int J Transgend Health, 26(1), 198-214. https://doi.org/10.1080/26895269.2024.2415681

Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study.

BACKGROUND: Although immune checkpoint inhibitors (ICIs) and anti-angiogenic drugs have demonstrated effectiveness in treating advanced gastric cancer (GC), their role in neoadjuvant or conversion the…

Thérapies de Conversion
Zhan, Z., Chen, B., Xu, S., Lin, R., Chen, H., Ma, X., Lin, X., Huang, W., Zhuo, C., Chen, Y., & Guo, Z. (2025). Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective cohort study.. Front Immunol, 16, 1518217. https://doi.org/10.3389/fimmu.2025.1518217

Conversion Therapy for Stage IV Gastric Cancer: Report From the Expert Consensus Meeting at KINGCA WEEK 2024.

Conversion therapy is a treatment strategy that shifts from palliative systemic therapy to curative surgical treatment for primary and/or metastatic stage IV gastric cancer (GC). To address its clinic…

Thérapies de Conversion
Kim, T. H., Uyama, I., Rha, S. Y., Bencivenga, M., An, J., Wyrwicz, L., Koo, D. H., van, H. i. l. l. e. g. e. r. s. b. e. r. g. . R., Lee, K. W., Li, G., Yoshikawa, T., Badgwell, B., Lorenzen, S., Kim, I. H., Lee, I. S., Han, H. S., & Hoon, H. (2025). Conversion Therapy for Stage IV Gastric Cancer: Report From the Expert Consensus Meeting at KINGCA WEEK 2024.. J Gastric Cancer, 25(1), 133-152. https://doi.org/10.5230/jgc.2025.25.e9

Surgical resection versus thermal ablation: comparison of sequential options after successful TACE downstaging therapy for unresectable hepatocellular carcinoma.

BACKGROUND: Transarterial chemoembolization (TACE) is an effective and safe downstaging therapy for hepatocellular carcinoma (HCC). However, the selection of sequential therapeutic modalities is still…

Thérapies de Conversion
An, C., Wu, S., Zuo, M., Li, W., Li, K., & Wu, P. (2025). Surgical resection versus thermal ablation: comparison of sequential options after successful TACE downstaging therapy for unresectable hepatocellular carcinoma.. Ther Adv Med Oncol, 17, 17588359241306648. https://doi.org/10.1177/17588359241306648

Prognosis predictors of hepatocellular carcinoma after hepatectomy following conversion therapy.

BACKGROUND: Hepatectomy is the optimal treatment for less than 20 % patients with hepatocellular carcinoma (HCC). A combination of hepatic artery infusion chemotherapy and systemic therapy-based conve…

Thérapies de Conversion
Liu, S., Wu, Z., Wang, C., Qiao, L., Huang, Z., Yuan, Y., Zou, R., He, W., Li, B., Yuan, Y., & Qiu, J. (2025). Prognosis predictors of hepatocellular carcinoma after hepatectomy following conversion therapy.. Eur J Surg Oncol, 51(1), 109375. https://doi.org/10.1016/j.ejso.2024.109375