Association of 10 VEGF Family Genes with Alzheimer's Disease Endophenotypes at Single Cell Resolution.

The cell-type specific role of the vascular endothelial growth factors (VEGFs) in the pathogenesis of Alzheimer's disease (AD) is not well characterized. In this study, we utilized a single-nucleus RN…

Neurosciences des Croyances
Wu, Y., Libby, J. B., Dumitrescu, L., De, J. a. g. e. r. . P. L., Menon, V., Schneider, J. A., Bennett, D. A., & Hohman, T. J. (2024). Association of 10 VEGF Family Genes with Alzheimer's Disease Endophenotypes at Single Cell Resolution.. bioRxiv. https://doi.org/10.1101/2024.04.12.589221

Internet Altruistic Behaviors in Adolescents: Roles of Attention-Deficit/Hyperactivity Disorder, Impulsiveness, and Perceived Social Support.

This study examined the associations of an attention-deficit/hyperactivity disorder (ADHD) diagnosis, impulsivity, and perceived social support with Internet altruistic behaviors (IABs) in adolescents…

Soutien par les pairs en ligne et transitions religieuses chez les adolescents
Peng, P. H., Chen, Y. L., Hsiao, R. C., Yen, C. F., & Chou, W. J. (2024). Internet Altruistic Behaviors in Adolescents: Roles of Attention-Deficit/Hyperactivity Disorder, Impulsiveness, and Perceived Social Support.. Behav Sci (Basel), 14(6). https://doi.org/10.3390/bs14060433

Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of neuropathology.

Recent evidence suggests that Alzheimer's disease (AD) genetic risk variants (rs1582763 and rs6591561) of the MS4A locus are genome-wide significant regulators of soluble TREM2 levels such that the mi…

Neurosciences des Croyances
Winfree, R. L., Nolan, E., Dumitrescu, L., Blennow, K., Zetterberg, H., Gifford, K. A., Pechman, K. R., Seto, M., Petyuk, V. A., Wang, Y., Schneider, J., Bennett, D. A., Jefferson, A. L., Hohman, T. J., & Alzheimer’s, D. i. s. e. a. s. e. . N. e. u. r. o. i. m. a. g. i. n. g. . I. n. i. t. i. a. t. i. v. e. *. (2024). Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of neuropathology.. Mol Neurodegener, 19(1), 41. https://doi.org/10.1186/s13024-024-00727-7

Feasibility of Fit24, a Digital Diabetes Prevention Program for Hispanic Adolescents: Qualitative Evaluation Study.

BACKGROUND: Digital health interventions are promising for reaching and engaging high-risk youth in disease prevention opportunities; however, few digital prevention interventions have been developed …

Soutien par les pairs en ligne et transitions religieuses chez les adolescents
Soltero, E. G., Musaad, S. M., O'Connor, T. M., Thompson, D., Norris, K., & Beech, B. M. (2024). Feasibility of Fit24, a Digital Diabetes Prevention Program for Hispanic Adolescents: Qualitative Evaluation Study.. JMIR Form Res, 8, e54595. https://doi.org/10.2196/54595

Options and survival benefits of conversion therapy for unresectable hepatocellular carcinoma.

In the study by Wu , patients with unresectable hepatocellular carcinoma were subjected to transarterial chemoembolization (TACE) as a conversion therapy in order to render their tumors suitable for r…

Thérapies de Conversion
She, W. H., & Cheung, T. T. (2024). Options and survival benefits of conversion therapy for unresectable hepatocellular carcinoma.. World J Gastroenterol, 30(18), 2479-2481. https://doi.org/10.3748/wjg.v30.i18.2479

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD.

BACKGROUND: Cellular senescence is a hallmark of aging and has been implicated in Alzheimer's disease (AD) pathogenesis. Cholesterol accumulation drives cellular senescence; however, the underlying me…

Neurosciences des Croyances
Wang, S., Li, B., Cai, Z., Hugo, C., Li, J., Sun, Y., Qian, L., Remaley, A. T., Tcw, J., Chui, H. C., Bennett, D. A., Arvanitakis, Z., Kerman, B., & Yassine, H. (2024). Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD.. Res Sq. https://doi.org/10.21203/rs.3.rs-4373201/v1

Assessment of the impact of COVID-19 and political instability on mental health of university students in Sudan.

BACKGROUND: The mental health of students plays a crucial role in their learning and performance. The COVID-19 pandemic, the political turmoil and a coup in Sudan has exacerbated stress and anxiety am…

Trauma Psychologique Religieux
Mohamed, M. S., Panda, D. S., Fadul, F. A., Saadeldin, A. A., Idriss, M. T., Khan, Y. H., Hussain, M. A., & Mallhi, T. H. (2024). Assessment of the impact of COVID-19 and political instability on mental health of university students in Sudan.. East Mediterr Health J, 30(4), 272-282. https://doi.org/10.26719/2024.30.4.272

Analysis of causal relations between vaccine hesitancy for COVID-19 vaccines and ideological orientations in Brazil.

This article presents a causal inference analysis of vaccine hesitancy for Coronavirus disease 2019 (COVID-19) vaccines based on socio-demographic data obtained via questionnaires applied to a sample …

Biais Cognitifs et Croyances
Pereira, E. T., Iasulaitis, S., & Greco, B. C. (2024). Analysis of causal relations between vaccine hesitancy for COVID-19 vaccines and ideological orientations in Brazil.. Vaccine, 42(13), 3263-3271. https://doi.org/10.1016/j.vaccine.2024.04.022

Spiritual Distress, Hopelessness, and Depression in Palliative Care: Simultaneous Concept Analysis.

Spiritual distress, hopelessness, and depression are concepts that are often used in palliative care. A simultaneous concept analysis (SCA) of these concepts is needed to clarify the terminology used …

Neurosciences des Croyances
Martins, H., Silva, R. S., Bragança, J., Romeiro, J., & Caldeira, S. (2024). Spiritual Distress, Hopelessness, and Depression in Palliative Care: Simultaneous Concept Analysis.. Healthcare (Basel), 12(10). https://doi.org/10.3390/healthcare12100960

Metabolic phenotyping reveals an emerging role of ammonia abnormality in Alzheimer's disease.

The metabolic implications in Alzheimer's disease (AD) remain poorly understood. Here, we conducted a metabolomics study on a moderately aging Chinese Han cohort (n = 1397; mean age 66 years). Conjuga…

Neurosciences des Croyances
Chen, T., Pan, F., Huang, Q., Xie, G., Chao, X., Wu, L., Wang, J., Cui, L., Sun, T., Li, M., Wang, Y., Guan, Y., Zheng, X., Ren, Z., Guo, Y., Wang, L., Zhou, K., Zhao, A., Guo, Q., … Jia, W. (2024). Metabolic phenotyping reveals an emerging role of ammonia abnormality in Alzheimer's disease.. Nat Commun, 15(1), 3796. https://doi.org/10.1038/s41467-024-47897-y

PReventing and Approaching Crises for frail community-dwelling patients Through Innovative Care (PRACTIC): protocol for an effectiveness cluster randomised controlled trial.

BACKGROUND: Demographic changes, with an increasing number and proportion of older people with multimorbidity and frailty, will put more pressure on home care services in municipalities. Frail multimo…

Recherche Participative avec Personnes Concernées
Væringstad, A., Dalbak, E. T. G., Holle, D., Myhre, J., Kirkevold, Ã. ˜., Bergh, S., & Lichtwarck, B. (2024). PReventing and Approaching Crises for frail community-dwelling patients Through Innovative Care (PRACTIC): protocol for an effectiveness cluster randomised controlled trial.. Trials, 25(1), 304. https://doi.org/10.1186/s13063-024-08117-6

Feasibility and Acceptability of a Meditation Mobile App Intervention for Adolescent and Young Adult Survivors of Childhood Cancer.

BACKGROUND: Adolescent and young adult (AYA) survivors of childhood cancer are increasingly recognized as a vulnerable group with unique emotional, social, and practical needs due to the intersection …

Soutien par les pairs en ligne et transitions religieuses chez les adolescents
Kwok, G., Sharma, A., Mandato, I., & Devine, K. A. (2024). Feasibility and Acceptability of a Meditation Mobile App Intervention for Adolescent and Young Adult Survivors of Childhood Cancer.. Int J Environ Res Public Health, 21(5). https://doi.org/10.3390/ijerph21050584