Case report: hepatic arterial infusion chemotherapy combined with sintilimab and lenvatinib for conversion therapy of colorectal cancer liver metastases.

BACKGROUND: Liver metastasis is one of the most common causes of death in patients with colorectal cancer. Therefore, improving the treatment effect of liver metastatic carcinoma of colorectal cancer …

Thérapies de Conversion
Peng, K., Li, Y., Su, H., Lan, C., Huang, Z., Wei, Y., Liao, X., Peng, M., Peng, T., & Zhu, G. (2023). Case report: hepatic arterial infusion chemotherapy combined with sintilimab and lenvatinib for conversion therapy of colorectal cancer liver metastases.. Front Immunol, 14, 1325445. https://doi.org/10.3389/fimmu.2023.1325445

Clinical Complete Response After Conversion Therapy for Unresectable Hepatocellular Carcinoma: Is Salvage Hepatectomy Necessary?

BACKGROUND: This study aimed to determine whether salvage hepatectomy offers prognostic advantages for unresectable hepatocellular carcinoma (uHCC) patients with clinical complete response (cCR) after…

Thérapies de Conversion
Wu, J. Y., Wu, J. Y., Liu, D. Y., Li, H., Zhuang, S. W., Li, B., Zhou, J. Y., Huang, J. Y., Zhang, Z. B., Li, S. Q., Yan, M. L., & Wang, Y. D. (2023). Clinical Complete Response After Conversion Therapy for Unresectable Hepatocellular Carcinoma: Is Salvage Hepatectomy Necessary?. J Hepatocell Carcinoma, 10, 2161-2171. https://doi.org/10.2147/JHC.S442341

Conversion therapy with immunotherapy plus chemotherapy achieves a pathological complete response in stage IIIC NSCLC.

As stage IIIC non-small cell lung cancer (NSCLC) is not recommended for surgical resection, the survival and prognosis for stage IIIC NSCLC remain poor. More powerful and individualized therapies are …

Thérapies de Conversion
Fu, Y., Duan, W., Xu, R., & Chen, J. (2023). Conversion therapy with immunotherapy plus chemotherapy achieves a pathological complete response in stage IIIC NSCLC.. Front Immunol, 14, 1268153. https://doi.org/10.3389/fimmu.2023.1268153

Medical students' perceptions of LGBTQ+ healthcare in Singapore and the United Kingdom.

INTRODUCTION: Lesbian, gay, bisexual, transgender, queer, and other sexual and gender minority (LGBTQ+) individuals have an increased scope of healthcare needs and face many barriers to accessing heal…

Thérapies de Conversion
Fu, M. X., Zou, T., Aiyappan, R., Ye, X., Onanuga, S., Tan, A., Smith, S., & Baptista, A. (2023). Medical students' perceptions of LGBTQ+ healthcare in Singapore and the United Kingdom.. Front Med (Lausanne), 10, 1236715. https://doi.org/10.3389/fmed.2023.1236715

Hepatic Artery Infusion Chemotherapy Sequential Hepatic Artery Embolization Combined with Operation in the Treatment of Recurrent Massive Hepatocellular Carcinoma Achieved Pathological Complete Response: A Case Report.

Hepatocellular carcinoma (HCC) recurrence, which encompasses both true recurrence resulting from cancer spread and de novo tumors developing within the same cancer-prone liver, presents a complication…

Thérapies de Conversion
Chen, J., Liao, X., Wu, Y., Ou, S., Qin, W., Yang, C., Tan, Y., Lao, Q., Peng, M., Peng, T., & Ye, X. (2023). Hepatic Artery Infusion Chemotherapy Sequential Hepatic Artery Embolization Combined with Operation in the Treatment of Recurrent Massive Hepatocellular Carcinoma Achieved Pathological Complete Response: A Case Report.. Pharmgenomics Pers Med, 16, 949-958. https://doi.org/10.2147/PGPM.S426791

Case Report: Successful conversion and salvage resection of huge hepatocellular carcinoma with portal vein tumor thrombosis and intrahepatic metastasis via sequential hepatic arterial infusion chemotherapy, lenvatinib plus PD-1 antibody followed by simult

BACKGROUND: Advanced hepatocellular carcinoma (HCC) shows poor prognosis. Combined hepatic artery infusion chemotherapy (HAIC) and lenvatinib and PD-1 antibody therapy show promising effects in treati…

Thérapies de Conversion
Luo, X., Chang, R. Z., Kuang, D., Yuan, M., Li, G. X., Zhang, B., Wang, Y. J., Zhang, W. G., & Ding, Z. Y. (2023). Case Report: Successful conversion and salvage resection of huge hepatocellular carcinoma with portal vein tumor thrombosis and intrahepatic metastasis via sequential hepatic arterial infusion chemotherapy, lenvatinib plus PD-1 antibody followed by simult. Front Immunol, 14, 1285296. https://doi.org/10.3389/fimmu.2023.1285296

Study protocol of a phase II clinical trial evaluating the efficacy of neoadjuvant intraperitoneal and systemic albumin-bound paclitaxel combined with camrelizumab and S-1 in the treatment of patients with exfoliative cell-positive gastric cancer.

BACKGROUND: Currently, gastric cancer with positive lavage cytology without gross peritoneal dissemination (GC-CY1) is a special type of metastatic form with poor prognosis. Consensus guidelines on tr…

Thérapies de Conversion
Lv, J., Wu, J., Wu, H., Ding, P., Guo, H., Yang, P., Tian, Y., Liu, Y., & Zhao, Q. (2023). Study protocol of a phase II clinical trial evaluating the efficacy of neoadjuvant intraperitoneal and systemic albumin-bound paclitaxel combined with camrelizumab and S-1 in the treatment of patients with exfoliative cell-positive gastric cancer.. Front Oncol, 13, 1201928. https://doi.org/10.3389/fonc.2023.1201928

Hepatectomy After Conversion Therapy with Hepatic Arterial Infusion Chemotherapy, Tyrosine Kinase Inhibitors and Anti-PD-1 Antibodies for Initially Unresectable Hepatocellular Carcinoma.

BACKGROUND: Most patients with hepatocellular carcinoma (HCC) are not candidates for liver resection. We investigated the clinicopathological characteristics and prognosis of patients with initially u…

Thérapies de Conversion
Yu, B., Zhang, N., Feng, Y., Zhang, Y., Zhang, T., & Wang, L. (2023). Hepatectomy After Conversion Therapy with Hepatic Arterial Infusion Chemotherapy, Tyrosine Kinase Inhibitors and Anti-PD-1 Antibodies for Initially Unresectable Hepatocellular Carcinoma.. J Hepatocell Carcinoma, 10, 1709-1721. https://doi.org/10.2147/JHC.S432062

Case Report: Camrelizumab combined with gemcitabine and oxaliplatin in the treatment of advanced intrahepatic cholangiocarcinoma: a case report and literature review.

Intrahepatic cholangiocarcinoma (ICC) is one of the most common invasive malignant tumors, with a 5-year survival rate of less than 5%. Currently, radical surgical resection is the preferred treatment…

Thérapies de Conversion
Zhang, Z., Wang, X., Li, H., Sun, H., Chen, J., & Lin, H. (2023). Case Report: Camrelizumab combined with gemcitabine and oxaliplatin in the treatment of advanced intrahepatic cholangiocarcinoma: a case report and literature review.. Front Immunol, 14, 1230261. https://doi.org/10.3389/fimmu.2023.1230261

Safety and efficacy of transarterial chemoembolization combined with tyrosine kinase inhibitors and camrelizumab in the treatment of patients with advanced unresectable hepatocellular carcinoma.

OBJECTIVE: This study was aimed to evaluate the efficacy and safety of transarterial chemoembolization combined with tyrosine kinase inhibitors and camrelizumab in the treatment of unresectable hepato…

Thérapies de Conversion
Li, J., Kong, M., Yu, G., Wang, S., Shi, Z., Han, H., Lin, Y., Shi, J., & Song, J. (2023). Safety and efficacy of transarterial chemoembolization combined with tyrosine kinase inhibitors and camrelizumab in the treatment of patients with advanced unresectable hepatocellular carcinoma.. Front Immunol, 14, 1188308. https://doi.org/10.3389/fimmu.2023.1188308

Laparoscopic Hepatectomy versus Open Hepatectomy After Conversion Therapy Using Transarterial Chemoembolization or Hepatic Arterial Infusion Chemotherapy for Patients with Initially Unresectable Hepatocellular Carcinoma.

BACKGROUND: Laparoscopic hepatectomy (LH) is more advantageous than open hepatectomy (OH) for hepatocellular carcinoma (HCC). However, surgical methods of conversion resection for patients with HCC ha…

Thérapies de Conversion
Yang, Z., Hu, Z., Fu, Y., Hu, D., Zhou, Z., Chen, M., Pan, Y., & Zhang, Y. (2023). Laparoscopic Hepatectomy versus Open Hepatectomy After Conversion Therapy Using Transarterial Chemoembolization or Hepatic Arterial Infusion Chemotherapy for Patients with Initially Unresectable Hepatocellular Carcinoma.. J Hepatocell Carcinoma, 10, 1157-1167. https://doi.org/10.2147/JHC.S417739

Case Report: A case of hepatocellular carcinoma with aberrant right hepatic artery treated with transarterial chemoembolization and infusion chemotherapy separately to bilobar lesion combining with systemic therapies and sequential hepatectomy.

BACKGROUND: Hepatocellular carcinoma (HCC) with a dismal prognosis is the second most deadly malignancy globally. Surgery is believed to be a curative approach. Nevertheless, there is still a consider…

Thérapies de Conversion
Wei, Y. G., Su, H., Lv, Z. L., Liao, X. W., Zeng, Z. M., Jia, Y. X., Huang, H. S., Shen, X. Q., Zhu, G. Z., Han, C. Y., Ye, X. P., & Peng, T. (2023). Case Report: A case of hepatocellular carcinoma with aberrant right hepatic artery treated with transarterial chemoembolization and infusion chemotherapy separately to bilobar lesion combining with systemic therapies and sequential hepatectomy.. Front Oncol, 13, 1165538. https://doi.org/10.3389/fonc.2023.1165538