Clinical Efficacy Exploration of Temperature-Sensitive Embolic Agent TACE Combined with HAIC and Targeted/Immunotherapy for Unresectable Primary Liver Cancer.

OBJECTIVE: To evaluate the efficacy and safety of TEM-TACE combined with HAIC and targeted/immunotherapy for the treatment of unresectable primary liver cancer, and to clarify the clinical application…

Thérapies de Conversion
Chen, X., Xiao, H., Lan, X., & Du, C. (2026). Clinical Efficacy Exploration of Temperature-Sensitive Embolic Agent TACE Combined with HAIC and Targeted/Immunotherapy for Unresectable Primary Liver Cancer.. J Hepatocell Carcinoma, 13, 572484. https://doi.org/10.2147/JHC.S572484

Pathologic response and safety of preoperative treatment regimens in gastric cancer undergoing D2 gastrectomy: a real-world cohort study.

OBJECTIVE: To compare pathological response and safety among three preoperative treatment regimens-chemotherapy alone, chemotherapy plus immunotherapy, and chemotherapy plus immunotherapy and targeted…

Thérapies de Conversion
Liu, P., Li, N., Guo, J., Wang, J., Wang, Z., Zhao, G., Mou, Z., & Mao, J. (2026). Pathologic response and safety of preoperative treatment regimens in gastric cancer undergoing D2 gastrectomy: a real-world cohort study.. Front Immunol, 17, 1766793. https://doi.org/10.3389/fimmu.2026.1766793

Surgery vs. non-surgery for advanced cholangiocarcinoma post-conversion therapy with PD-1/PD-L1 inhibitors plus TKIs.

OBJECTIVE: To compare overall survival (OS) and progression-free survival (PFS) between surgical resection and non-surgical therapy in initially unresectable Cholangiocarcinoma (CCA) patients who achi…

Thérapies de Conversion
Sun, Z., Wang, Y., Chen, X., Yang, L., Li, O., Zhou, J., Tan, Z., & Peng, C. (2026). Surgery vs. non-surgery for advanced cholangiocarcinoma post-conversion therapy with PD-1/PD-L1 inhibitors plus TKIs.. Front Immunol, 17, 1753437. https://doi.org/10.3389/fimmu.2026.1753437

Sexual Orientation and Gender Identity Change Efforts Before Age 18: Demographic Correlates and Associations with Mental Health Conditions.

PURPOSE: We examined the associations of sexual orientation and gender identity change efforts (SOGICE), both experienced over the lifetime and before adulthood, with demographic characteristics and a…

Thérapies de Conversion
Xu, Y., Hall, W. J., Wilson, J., & Russell, S. T. (2026). Sexual Orientation and Gender Identity Change Efforts Before Age 18: Demographic Correlates and Associations with Mental Health Conditions.. LGBT Health, 13(2), 85-92. https://doi.org/10.1177/23258292251413624

Clinical outcomes with first-line tislelizumab plus lenvatinib in unresectable hepatocellular carcinoma: a retrospective analysis.

PURPOSE: This retrospective analysis aimed to assess the therapeutic efficacy and adverse event profile of tislelizumab combined with lenvatinib in patients with unresectable hepatocellular carcinoma …

Thérapies de Conversion
Lin, J., Zhou, Q., Yao, Z., Wang, Q., Xu, S., Xiong, Z., Dang, X., Liang, H., & Liu, B. (2026). Clinical outcomes with first-line tislelizumab plus lenvatinib in unresectable hepatocellular carcinoma: a retrospective analysis.. PeerJ, 14, e20591. https://doi.org/10.7717/peerj.20591

A clinical-molecular nomogram for predicting early recurrence following resection of initially unresectable colorectal liver metastases.

BACKGROUND: Postoperative early recurrence (PER) remains a major challenge to long-term survival after successful conversion therapy and curative resection for initially unresectable colorectal liver …

Thérapies de Conversion
Lu, Y. T., Huang, X. X., Chen, W. C., Xiao, Q. Y., Duan, J. L., Li, Z. J., Pat, F. o. n. g. . W., Wang, F. H., Li, Y. H., & Wang, D. S. (2026). A clinical-molecular nomogram for predicting early recurrence following resection of initially unresectable colorectal liver metastases.. Ther Adv Med Oncol, 18, 17588359251411660. https://doi.org/10.1177/17588359251411660

From Control to Conversion: Optimizing Systemic Therapy for Curative-Intent Conversion Surgery in Metastatic Gastric Cancer.

Conversion therapy enables curative-intent resection in patients with initially unresectable or metastatic cancers after effective systemic therapy. Recently, advances in systemic therapy with molecul…

Thérapies de Conversion
Han, H. S., & Rha, S. Y. (2026). From Control to Conversion: Optimizing Systemic Therapy for Curative-Intent Conversion Surgery in Metastatic Gastric Cancer.. J Gastric Cancer, 26(1), 146-160. https://doi.org/10.5230/jgc.2026.26.e8

Response Rate Correlates with the Conversion Rate in Patients with Advanced Hepatocellular Carcinoma Treated with Systemic or Hepatic Artery Infusion Chemotherapy: A Systematic Review.

UNLABELLED: Introduction: The appropriate regimen for induction therapy with the intent of conversion therapy for advanced hepatocellular carcinoma (HCC) is unknown. This study aimed to evaluate wheth…

Thérapies de Conversion
Okuno, M., Nishino, H., Okura, K., Ishii, T., Hashida, H., & Hatano, E. (2026). Response Rate Correlates with the Conversion Rate in Patients with Advanced Hepatocellular Carcinoma Treated with Systemic or Hepatic Artery Infusion Chemotherapy: A Systematic Review.. Dig Surg, 43(1), 23-34. https://doi.org/10.1159/000550237

Safety and efficacy of conversion therapy for metastatic esophageal cancer: exploratory analysis of JCOG1314.

BACKGROUND: Recent advances in multimodal treatments indicate that conversion therapy (CT) is a viable option for metastatic esophageal cancer (EC). JCOG1314 was a randomized phase III trial to confir…

Thérapies de Conversion
Matsuda, S., Tsushima, T., Kawakubo, H., Hironaka, S., Tsubosa, Y., Sakanaka, K., Oguma, J., Kadowaki, S., Tsunoda, S., Hara, H., Koyanagi, K., Yamaguchi, T., Harada, K., Takahashi, M., Minashi, K., Baba, E., Sasaki, K., Machida, R., & Takeuchi, H. (2026). Safety and efficacy of conversion therapy for metastatic esophageal cancer: exploratory analysis of JCOG1314.. Esophagus, 23(1), 111-119. https://doi.org/10.1007/s10388-025-01163-2

Impact of HER2 and microsatellite instability status on response to neoadjuvant/conversion therapy and survival in patients with gastric cancer.

OBJECTIVES: The prognostic significance of microsatellite instability (MSI) and HER2 status in advanced gastric cancer (AGC) treated with neoadjuvant or conversion chemotherapy (NAC) remains unclear. …

Thérapies de Conversion
Piccioni, S. A., Costantini, M., Petrioli, R., Bagnacci, G., Ferrara, D., Andreucci, E., Carbone, L., Ongaro, A., Calomino, N., Sandini, M., Mazzei, M. A., Roviello, F., & Marrelli, D. (2026). Impact of HER2 and microsatellite instability status on response to neoadjuvant/conversion therapy and survival in patients with gastric cancer.. Eur J Cancer Prev, 35(1), 66-77. https://doi.org/10.1097/CEJ.0000000000000982

A Qualitative Double Perspective Investigation of Sexual Orientation Change Efforts Among Homosexual Individuals in Tunisia.

Despite the condemnation of the major medical and psychological institutions, which warn of the significant harm associated with sexual orientation change efforts, these practices persist in certain c…

Thérapies de Conversion
Mahjoubi, H., Mtiraoui, A., & Préau, M. (2026). A Qualitative Double Perspective Investigation of Sexual Orientation Change Efforts Among Homosexual Individuals in Tunisia.. J Homosex, 73(5), 1270-1290. https://doi.org/10.1080/00918369.2025.2503407

"Backed into a Corner": Lived experiences of receiving and providing involuntary psychiatric treatment under British Columbia's Mental Health Act.

British Columbia's Mental Health Act permits the involuntarily detention and treatment of individuals who meet specific criteria. Over the past 15 years, British Columbia has seen an increasing trend …

Recherche Participative avec Personnes Concernées
Snow, M. E., Salmon, A., Banjo, J., Morrow, M., & Varcoe, C. (2026). "Backed into a Corner": Lived experiences of receiving and providing involuntary psychiatric treatment under British Columbia's Mental Health Act.. PLoS One, 21(6), e0329049. https://doi.org/10.1371/journal.pone.0329049