Experience of nulliparous patients aged <30 years seeking permanent female contraception: A qualitative study.

OBJECTIVE: This study aimed to describe the experience of nulliparous individuals aged

Études fondées sur les communautés Reddit
Meurice, M. E., Wallis-Lang, K., Hildebrand, M. C., Mackey, T. K., & Mody, S. K. (2025). Experience of nulliparous patients aged <30 years seeking permanent female contraception: A qualitative study.. Contraception, 150, 111010. https://doi.org/10.1016/j.contraception.2025.111010

Questionable 'Good Faith' Reporting: A Study of Web-Based Abuse Reporting in the Canadian Catholic Church.

The Roman Catholic Church provides a fruitful contextual basis for assessing good faith reporting of child sexual abuse. Drawing on the literature of organizational decoupling and organizational misco…

Violences Sexuelles en Contexte Sectaire
Driscoll, C., & Chigumba, C. C. (2025). Questionable 'Good Faith' Reporting: A Study of Web-Based Abuse Reporting in the Canadian Catholic Church.. J Child Sex Abus, 34(7), 776-795. https://doi.org/10.1080/10538712.2025.2574084

Conversion therapy of tislelizumab plus lenvatinib and GEMOX in unresectable locally advanced biliary tract cancer (ZSAB-TransGOLP): a multicentre, prospective, phase 2 study.

BACKGROUND: The optimal conversion regimen that allows more patients with unresectable biliary tract cancer to access surgery remains unclear; there is currently no standard conversion therapy for bil…

Thérapies de Conversion
Shi, G., Huang, X., Li, X., Liang, F., Gao, Q., Zhang, D., Lu, J., Ji, Y., Hu, Z., Chen, Y., Qiu, S., Yi, Y., Zhu, X., Sun, H., Shi, Y., Peng, M., Wang, X., Huang, C., Ding, Z., … Fan, J. (2025). Conversion therapy of tislelizumab plus lenvatinib and GEMOX in unresectable locally advanced biliary tract cancer (ZSAB-TransGOLP): a multicentre, prospective, phase 2 study.. Lancet Oncol, 26(10), 1334-1345. https://doi.org/10.1016/S1470-2045(25)00376-6

Conversion Therapy for Locally Advanced Intrahepatic Cholangiocarcinoma: A Retrospective Cohort Study.

BACKGROUND AND OBJECTIVES: Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant biliary tumor associated with a poor prognosis. Here, we explored conversion therapy (CT) for the treatment of l…

Thérapies de Conversion
Lu, J., Zhou, L., Zhang, S., Li, J., Liu, T., & Huang, B. (2025). Conversion Therapy for Locally Advanced Intrahepatic Cholangiocarcinoma: A Retrospective Cohort Study.. J Surg Oncol, 132(5), 917-923. https://doi.org/10.1002/jso.70068

[The research progress of neoadjuvant and conversion therapy in biliary tract carcinoma].

Biliary tract carcinoma (BTC) is a highly aggressive malignancy,and the majority of patients present with advanced stage at first diagnosis which resulting in poor prognosis. Traditional chemotherapy …

Thérapies de Conversion
Lan, C. L., Zeng, Z. M., Zhu, G. Z., & Peng, T. (2025). [The research progress of neoadjuvant and conversion therapy in biliary tract carcinoma].. Zhonghua Wai Ke Za Zhi, 63(10), 904-910. https://doi.org/10.3760/cma.j.cn112139-20250110-00015

Genomic and Clinical Predictors of Conversion in Initially Unresectable Colorectal Cancer Liver Metastases.

BACKGROUND: Colorectal cancer liver metastases (CRLM) present significant treatment challenges, requiring multimodal conversion therapies. Identifying factors that influence treatment outcomes is cruc…

Thérapies de Conversion
Zuo, D., Wang, L., Jin, K., Zhang, Y., Wang, Y., Sun, Y., & Tang, J. (2025). Genomic and Clinical Predictors of Conversion in Initially Unresectable Colorectal Cancer Liver Metastases.. Ann Surg Oncol, 32(10), 7173-7182. https://doi.org/10.1245/s10434-025-17809-5

CRABP2 promotes peritoneal metastasis in CRC through TGF-β/Smad-mediated EMT signaling and invadopodia formation.

Peritoneal metastasis (PM) in colorectal cancer (CRC) is typically associated with a lower likelihood of successful conversion therapy and a poorer prognosis compared to metastases at other sites. Inv…

Thérapies de Conversion
Hao, W., Dong, X., Wang, Z., Wen, T., Liu, L., Gu, T., & Ma, H. (2025). CRABP2 promotes peritoneal metastasis in CRC through TGF-β/Smad-mediated EMT signaling and invadopodia formation.. Cell Signal, 134, 111927. https://doi.org/10.1016/j.cellsig.2025.111927

Comparison of Efficacy between Lenvatinib and Bevacizumab in Combination of Immune Checkpoint Inhibitor and Interventional Triple Therapy in Chinese Advanced Hepatocellular Carcinoma: The CLEAP 2302 Study.

BACKGROUND: The conversion therapy for advanced hepatocellular carcinoma (HCC) shows promise with a triple therapy approach that combines interventional therapy, immune checkpoint inhibitors, and mole…

Thérapies de Conversion
Pan, Z., Liu, D., Cao, J., Fu, L., Zhang, X., Zhu, X., Pan, Y., Liu, J., Han, C., Jin, R., Shen, S., Zhang, X., Liu, H., Yang, X., Hu, K., Shi, X., Wang, D., Zhao, Y., Zhong, J., … China, L. i. v. e. r. . C. a. n. c. e. r. . S. t. u. d. y. . G. r. o. u. p. . Y. o. u. n. g. . I. n. v. e. s. t. i. g. a. t. o. r. s. . (. C. L. E. A. P. ). (2025). Comparison of Efficacy between Lenvatinib and Bevacizumab in Combination of Immune Checkpoint Inhibitor and Interventional Triple Therapy in Chinese Advanced Hepatocellular Carcinoma: The CLEAP 2302 Study.. Liver Cancer, 14(5), 601-619. https://doi.org/10.1159/000545545

"I miss stars, too": a thematic analysis of the experiences of persons with retinitis pigmentosa using Reddit.

Retinitis pigmentosa (RP) is a progressive retinal disorder that affects the emotional, psychological, and social lives of those afflicted. With limited effective treatments, understanding the persona…

Études fondées sur les communautés Reddit
Ng, Q. X., Chan, H. W., & Koh, G. C. H. (2025). "I miss stars, too": a thematic analysis of the experiences of persons with retinitis pigmentosa using Reddit.. J Community Genet, 16(5), 539-544. https://doi.org/10.1007/s12687-025-00796-1

The immune-reinforcements of Lenvatinib plus anti-PD-1 and their rationale to unite with TACE for unresectable hepatocellular carcinoma treatment.

BACKGROUND: Despite encouraging clinical benefits have gained by anti-PD-1 and Lenvatinib combination, in-depth characterizations about the mechanisms of action remain poorly characterized. Furthermor…

Thérapies de Conversion
Jiang, J., Zhang, H., Ou, Y., Lai, J., Huang, Y., Cai, W., Li, C., Zhang, L., & Fu, Y. (2025). The immune-reinforcements of Lenvatinib plus anti-PD-1 and their rationale to unite with TACE for unresectable hepatocellular carcinoma treatment.. Immunol Lett, 275, 107003. https://doi.org/10.1016/j.imlet.2025.107003

Glial Cell Reprogramming in Ischemic Stroke: A Review of Recent Advancements and Translational Challenges.

Ischemic stroke, the second leading cause of death worldwide and the leading cause of long-term disabilities, presents a significant global health challenge, particularly in aging populations where th…

Thérapies de Conversion
Greșiță, A., Hermann, D. M., Boboc, I. K. S., Doeppner, T. R., Petcu, E., Semida, G. F., & Popa-Wagner, A. (2025). Glial Cell Reprogramming in Ischemic Stroke: A Review of Recent Advancements and Translational Challenges.. Transl Stroke Res, 16(5), 1811-1835. https://doi.org/10.1007/s12975-025-01331-7

Evaluation of a 'Research Methods' Training Course for Novice Lived Experience Researchers.

BACKGROUND: The training of lived experience researchers (LERs) for involvement in research design and conduct is a key principle to its success. However, little is known about what research methods t…

Expertise Expérientielle et Savoirs Situés
Grundy, A. C., Bhutta, A., Mahyoub, A., Jenkins, R., Mir, S., Miah, J., Faragher, G., & Lovell, K. (2025). Evaluation of a 'Research Methods' Training Course for Novice Lived Experience Researchers.. Health Expect, 28(5), e70362. https://doi.org/10.1111/hex.70362